Evidence map›Paper›PMID 41276743›Full record

SynthesisJournal of cachexia, sarcopenia and muscle2025

Psychometric Properties of the SarQoL Questionnaire: A Systematic Review and Meta-Analysis.

Céline Demonceau, Brabant Christian, Shukuru Emmanuel, Majed Alokail, Nasser Al-Daghri, Yves Rolland, Ivan Bautmans, Jürgen M Bauer, Antonio Cherubini, Alfonso J Cruz-Jentoft and 10 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of cachexia, sarcopenia and muscle, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Céline DemonceauResearch Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.ORCID 0000-0001-7089-6605
Brabant ChristianResearch Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Shukuru EmmanuelPublic Health Aging Research & Epidemiology (PHARE)Group, Research Unit in Clinical Pharmacologyand Toxicology (URPC), Department of Biomedical Sciences‑Faculty of Medicine, NAmur Research Institute for LIfeSciences (NARILIS), University of Namur, Namur, Belgium.
Majed AlokailProtein Research Chair, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0001-6049-4637
Nasser Al-DaghriProtein Research Chair, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0001-5472-1725
Yves RollandIHU HealthAge, Gérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France.ORCID 0000-0002-1157-0215
Ivan BautmansGerontology Department and Frailty in Ageing Research Department, Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-6820-9586
Jürgen M BauerCenter for Geriatric Medicine and Network Aging Research (NAR), Heidelberg University, Heidelberg, Germany.
Antonio CherubiniGeriatria, Accettazione Geriatrica e Centro di Ricerca per l'Invecchiamento, IRCCS INRCA, Ancona, Italy.ORCID 0000-0003-0261-9897
Alfonso J Cruz-JentoftServicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.
Bess Dawson-HughesJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.ORCID 0000-0003-3136-0386
Roger A FieldingNutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Centeron Aging, Tufts University, Boston, Massachusetts, USA.ORCID 0000-0003-2236-9020
Nicholas C HarveyMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.ORCID 0000-0002-8194-2512
Francesco LandiFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Marjolein VisserDepartment of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam and the Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.ORCID 0000-0002-5136-298X
Gustavo DuqueBone, Muscle & Geroscience Group, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
René RizzoliService of Bone Diseases, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.ORCID 0000-0002-1537-422X
Jean-Yves ReginsterProtein Research Chair, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0001-6290-752X
Olivier BruyèreResearch Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.ORCID 0000-0003-4269-9393
Charlotte BeaudartPublic Health Aging Research & Epidemiology (PHARE)Group, Research Unit in Clinical Pharmacologyand Toxicology (URPC), Department of Biomedical Sciences‑Faculty of Medicine, NAmur Research Institute for LIfeSciences (NARILIS), University of Namur, Namur, Belgium.ORCID 0000-0002-0827-5303

Funding

TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI LEWIS LIPSITZ · 2008 to 2026
$23.9M
NIA NIH HHS P30 AG031679NIH Boston Claude D. Pepper Center 1P30AG031679US Department of Agriculture (USDA) 58-8050-3-003
6 · The paper itself

Abstract

backgroundThe Sarcopenia and Quality of Life (SarQoL) questionnaire is recognized as the only disease-specific patient-reported outcome measure (PROM) for assessing sarcopenia-related HRQoL. This systematic review and meta-analysis aimed to provide a quantitative summary of all evidence reported on the reliability, validity, responsiveness and floor/ceiling effects of SarQoL in older adults.

methodsFollowing PRISMA-COSMIN guidelines, a systematic search for studies evaluating the psychometric properties of SarQoL (i.e., reliability, validity, responsiveness and floor and ceiling effects) in older people was conducted on MEDLINE (via OVID), PsycINFO, Scopus and EMBASE. Studies published between 2013 and November 2024 using a consensual definition of sarcopenia were included. Study selection and data extraction were made by two independent reviewers. A random-effects model meta-analysis was applied. PROSPERO registration: CRD42024546880.

resultsFrom 411 studies identified by the search strategy, 25 fulfilled the inclusion criteria, including 4585 community-dwelling individuals, of which 1311 were diagnosed as sarcopenic. SarQoL demonstrated high reliability (pooled Cronbach's alpha values consistently exceeding 0.80) and excellent test-retest reliability (pooled ICC = 0.98). Construct validity was confirmed with strong convergent correlations (pooled r > 0.54) with related dimensions of generic SF-36 and EQ-5D and weaker divergent correlations (pooled r < 0.47). Responsiveness, evaluated in two studies using different methodologies, supported the ability of SarQoL to detect meaningful changes in HRQoL. The certainty of evidence was rated as high for reliability, validity and responsiveness.

conclusionThis meta-analysis consolidates a decade of evidence and confirms the strong psychometric properties of SarQoL, with a high level of evidence.

Indexed as

PsychometricsQuality of LifeSarcopeniaAgedHumansReproducibility of ResultsSurveys and Questionnairesmeta‐analysisPROMspsychometric propertiesquality of lifesarcopeniaSarQoL

Identifiers

PMID41276743
PMCPMC12646114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.