Evidence map›Paper›PMID 41276675›Full record

ArticleVirchows Archiv : an international journal of pathology2025

Splenosis involved by in situ follicular B-cell neoplasm.

Mahreen Hussain, Kseniia Malkova, Aleksandr Romanov, Faisal Rawas, Gulrukh K Botiralieva, Natalya Pak, Yaroslav N Chernov, Kirill A Lyapichev

Abstract read
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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Omental Splenosis Mimicking Peritoneal Carcinomatosis.Mediterranean journal of hematology and infectious diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahreen HussainDepartment of Anatomical and Clinical Pathology, The University of Texas Medical Branch, Galveston, TX, USA.
Kseniia MalkovaDepartment of Anatomical and Clinical Pathology, The University of Texas Medical Branch, Galveston, TX, USA.
Aleksandr RomanovDepartment of Anatomical and Clinical Pathology, The University of Texas Medical Branch, Galveston, TX, USA.
Faisal RawasDepartment of Anatomical and Clinical Pathology, The University of Texas Medical Branch, Galveston, TX, USA.
Gulrukh K BotiralievaIPSUM Pathology LLC, Tashkent, Uzbekistan.
Natalya PakCentral Asian University, Tashkent, Uzbekistan.
Yaroslav N ChernovThe Institute for Urology and Reproductive Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Kirill A LyapichevDepartment of Anatomical and Clinical Pathology, The University of Texas Medical Branch, Galveston, TX, USA. LYAPICK@ccf.org.ORCID http://orcid.org/0000-0001-9983-9735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the first well-documented case of in situ follicular B-cell neoplasm (ISFN) arising in splenosis in a patient with a remote history of splenectomy. A 60-year-old man undergoing evaluation for hydrocele was incidentally found to have multiple mesenteric masses on imaging. His past surgical history was notable for splenectomy 40 years earlier following a motor vehicle accident. Biopsy of the largest mass revealed fragments of splenic parenchyma containing two small follicles infiltrated by atypical lymphocytes. Follicular architecture was preserved without expansion or disruption. Immunohistochemistry demonstrated that the neoplastic cells were positive for CD20, PAX5, CD10, BCL2, and BCL6 and negative for CD3 and CD5. Flow cytometry performed on a concurrent specimen identified a clonal CD10-positive aberrant B-cell population. Fluorescence in situ hybridization (FISH) revealed a chromosomal translocation, t(14;18). These findings supported a diagnosis of ISFN.

Indexed as

In situ follicular B-cell neoplasmMesenteric massSplenosis

Identifiers

PMID41276675

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.