Trial reportScientific reports2025
Lithium effects on impulsivity and emotional processing.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effects of acute ebselen add-on treatment on resting state function connectivity in depressed patients with inadequate response to antidepressants.Scientific reports · 2026Trial
- Association Between Lithium Use and Suicide-Related Behaviors in Bipolar Disorder: A Multicenter Study.Bipolar disorders · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lithium is an effective treatment for mood disorders. However, its mechanism of action concerning its effect on impulsivity and emotional processing is still unclear. The current study aimed to investigate the effect of a 5-day lithium treatment on decision-making, reward-seeking and emotional processing in healthy volunteers. We conducted a double-blind, placebo-controlled, cross-over design study involving sixteen participants aged 18-50 years. Participants received lithium 800 mg once daily followed by matching placebo or vice versa for five days in a random order. Impulsivity and emotional processing were assessed on day six using the Cambridge Gambling Task and the Emotional Testing Battery, respectively. There were significant interactions with large effect sizes between treatment and order for delay aversion (F
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.