Evidence map›Paper›PMID 41276576›Full record

ArticleScientific reports2025

Morphology dependent antibacterial activity of zinc oxide nanoparticles against clinically relevant bacteria.

Naila Zubair, Rasha Mohammed Sajet Al-Oqaili, Muhammad Junaid Yousaf, Aisha Siddique, Fuad A Awwad, Emad A A Ismail, Farrah Shams, Adil Aldhahrani, Nizwa Itrat, Farhad Ali and 7 more

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Naila ZubairDepartment of Chemistry, Women University Mardan, Mardan, Pakistan.
Rasha Mohammed Sajet Al-OqailiDepartment of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq.
Muhammad Junaid YousafDepartment of Botany, Government Post Graduate College, Mardan, Pakistan.
Aisha SiddiqueDepartment of Microbiology, Women University Mardan, Mardan, KP, Pakistan.
Fuad A AwwadDepartment of Quantitative Analysis, College of Business Administration, King Saud University, P.O. Box 71115, 11587, Riyadh, Saudi Arabia.
Emad A A IsmailDepartment of Quantitative Analysis, College of Business Administration, King Saud University, P.O. Box 71115, 11587, Riyadh, Saudi Arabia.
Farrah ShamsDepartment of Anatomy, General Medicine Program, Batterjee Medical College, 21442, Jeddah, Saudi Arabia.
Adil AldhahraniClinical Laboratory Sciences Department, Turabah University College, Taif University, 21995, Taif, Saudi Arabia.
Nizwa ItratInstitute of Home Science, University of Agriculture, Faisalabad, Pakistan.
Farhad AliInstitute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, Pakistan.
Devendra Pratap RaoCoordination Chemistry Laboratory, Department of Chemistry, Dayanand Anglo-Vedic (PG) College, Chhatrapati Shahu Ji Maharaj University, Kanpur, U.P., 208001, India.
Hina KhalidNational Centre of Excellence in Physical Chemistry, University of Peshawar, Peshawar, Pakistan.
Fawad AliInstitute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, Pakistan. fawadansi@gmail.com.
Fawziah A Al-SalmiDepartment of Biology, Faculty of Sciences, Taif University, 21944, Taif, Saudi Arabia.
Muneefah Abdullah AleneziDepartment of Biology, Faculty of Science, University of Tabuk, 71491, Tabuk, Kingdom of Saudi Arabia.
Husna Irfan ThalibGeneral Medicine Practice Program, Batterjee Medical College, Jeddah, Saudi Arabia.
Jumana Hussain TimrazGeneral Medicine Practice Program, Batterjee Medical College, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study focuses on the antibacterial activity of ZnO nanoparticles, evaluating variations based on morphology. Interest in ZnO nanoparticles arises from their high surface-to-volume ratio that enables effective interaction with bacterial cells. Their antibacterial properties depend on size and nanostructure, with enhanced activity attributed to increased surface area, promoting maximum contact with microbial membranes, cellular damage, and growth inhibition. Zinc oxide (ZnO) nanoparticles with two distinct shapes-ellipsoidal nanorods (Z1) and 3D microspheres (Z2)-were synthesized using a simple, template-free aqueous precipitation method. Zinc nitrate and hexamethylenetetramine (HMT) served as starting materials. The nanoparticles were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), and thermogravimetric analysis (TGA). The point of zero charge (PZC) was determined by the salt addition method. SEM images showed that particle shape changed with reaction time. XRD confirmed a hexagonal wurtzite crystal structure, with average crystallite sizes of 22.09 nm for Z1 and 27.18 nm for Z2. FT-IR spectra showed Zn-O bond vibrations between 540 and 411 cm

Indexed as

Anti-Bacterial AgentsBacteriaMetal NanoparticlesNanoparticlesZinc OxideEscherichia coliMicrobial Sensitivity TestsMicroscopy, Electron, ScanningParticle SizeSpectroscopy, Fourier Transform InfraredStaphylococcus aureusX-Ray DiffractionAnti-Bacterial AgentsZinc OxideAntibacterial activityControlled precipitation methodPoint of zero chargeZnO nanoparticlesZone of inhibition

Identifiers

PMID41276576
PMCPMC12749075

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.