Evidence map›Paper›PMID 41276522›Full record

ArticleScientific reports2025

Synthesis, characterization, computational and biological evaluation of pyrazole hydrazones as promising anti-inflammatory agents.

Hemant S Deshmukh, Vishnu A Adole, A Alfind Paul Frit, Suraj N Mali, Haya Khader Ahmad Yasin, Bhausaheb N Patil, S Janani, Bapu S Jagdale

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hemant S DeshmukhResearch Centre in Chemistry, Mahatma Gandhi Vidyamandir's Loknete Vyankatrao Hiray Arts, Science and Commerce College (Affiliated to Savitribai Phule Pune University, Pune), Panchavati, Nashik, 422003, Maharashtra, India.
Vishnu A AdoleResearch Centre in Chemistry, Mahatma Gandhi Vidyamandir's Loknete Vyankatrao Hiray Arts, Science and Commerce College (Affiliated to Savitribai Phule Pune University, Pune), Panchavati, Nashik, 422003, Maharashtra, India. vishnuadole86@gmail.com.ORCID http://orcid.org/0000-0001-7691-7884
A Alfind Paul FritDepartment of Physics, Vel Tech High Tech Dr.Rangarajan Dr.Sakunthala Engineering College, Avadi, Chennai, 600062, Tamil Nadu, India.
Suraj N MaliSchool of Pharmacy, DY Patil University, Navi Mumbai, 400706, Maharashtra, India.
Haya Khader Ahmad YasinDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, P.O. Box 346, Ajman, United Arab Emirates. Yasinh.yasin@ajman.ac.ae.ORCID http://orcid.org/0000-0002-1262-2507
Bhausaheb N PatilCSIR-National Chemical Laboratory, Pune, 411008, India.
S JananiDepartment of Physics, Meenakshi college for Women (Affiliated to University ofMadras, Chennai), Kodambakkam, Chennai, 600024, Tamil Nadu, India.
Bapu S JagdaleResearch Centre in Chemistry, Mahatma Gandhi Vidyamandir's Loknete Vyankatrao Hiray Arts, Science and Commerce College (Affiliated to Savitribai Phule Pune University, Pune), Panchavati, Nashik, 422003, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, two pyrazole-based hydrazone derivatives, 5-methyl-1-phenyl-4-(1-(2-phenylhydrazineylidene)ethyl)-1H-pyrazole (PMPH) and 1-(4-fluorophenyl)-5-methyl-4-(1-(2-phenylhydrazineylidene)ethyl)-1H-pyrazole (4F-PMPH), were synthesized and the structures of the compounds were elucidated through FT-IR,

Indexed as

Anti-Inflammatory AgentsHydrazonesPyrazolesAnimalsCattleCyclooxygenase 2Molecular Docking SimulationMolecular Dynamics SimulationSerum Albumin, BovineSpectroscopy, Fourier Transform InfraredAnti-Inflammatory AgentsCyclooxygenase 2HydrazonespyrazolePyrazolesSerum Albumin, BovineAnti-inflammatoryDensity functional theoryDrug designHydrazonePyrazole

Identifiers

PMID41276522
PMCPMC12657918

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.