Evidence map›Paper›PMID 41276512›Full record

ArticleNature communications2025

Mechano-bioactive hydrogel bioelectronics for mechanical-electrical-bioenergetic conversion and glia-modulating neural regeneration.

Junjie Shen, Shihao Wu, Yifan Wang, Zhiwen Yan, Tiexin Liu, Xiaodan Sun, Yun Qian

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junjie Shen *National Center for Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shihao Wu *School of Medicine, Yunnan University, Kunming, Yunnan, China.
Yifan Wang *State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, China.
Zhiwen YanNational Center for Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tiexin LiuNational Center for Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaodan SunState Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, China. sunxiaodan@tsinghua.edu.cn.ORCID http://orcid.org/0000-0001-8394-5920
Yun QianNational Center for Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. sakio@sjtu.edu.cn.ORCID http://orcid.org/0000-0003-1600-5693

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82372409
6 · The paper itself

Abstract

Dynamic mechanical cues are crucial for glial neuromodulation and energy metabolism in neural regeneration, yet the mechanisms underlying mechanotransduction and intracellular organelle responses in glia after neurotrauma remain vague. In this study, we develop mechano-bioactive piezoelectric hydrogel bioelectronics (BaTiO

Indexed as

HydrogelsMechanotransduction, CellularNerve RegenerationNeurogliaAnimalsAstrocytesDogsEnergy MetabolismMaleMiceRatsRats, Sprague-DawleySchwann CellsHydrogels

Identifiers

PMID41276512
PMCPMC12749645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.