Evidence map›Paper›PMID 41275917›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2026

Utilization of organs following implementation of the 2020 United States Public Health Service guideline recommendations.

Isabel Griffin, Ian Kracalik, Matthew Sapiano, Pallavi Annambhotla, James Bowman, Marilyn E Levi, Sridhar V Basavaraju

Abstract read
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In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isabel GriffinOffice of Blood, Organ, and Other Tissue Safety, Medical Product Safety Branch, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. Electronic address: pli7@cdc.gov.
Ian KracalikOffice of Blood, Organ, and Other Tissue Safety, Medical Product Safety Branch, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Matthew SapianoOffice of Blood, Organ, and Other Tissue Safety, Medical Product Safety Branch, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Pallavi AnnambhotlaOffice of Blood, Organ, and Other Tissue Safety, Medical Product Safety Branch, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
James BowmanDivision of Transplantation, Health Systems Bureau, Health Resources and Services Administration, Rockville, Maryland, USA.
Marilyn E LeviDivision of Transplantation, Health Systems Bureau, Health Resources and Services Administration, Rockville, Maryland, USA.
Sridhar V BasavarajuOffice of Blood, Organ, and Other Tissue Safety, Medical Product Safety Branch, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The 2013 U.S. Public Health Service (PHS) guideline for screening organ donors for human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) designated donors with social and behavioral characteristics associated with HIV, HBV, and HCV for transmission as increased risk donors (IRDs) and was associated with an underutilization of IRD organs. In 2020, the PHS guideline was updated to remove the IRD designation and certain risk factor criteria. We analyzed adult and pediatric organ transplantation from 2019 to 2023 to assess the impact of the 2020 guideline on organ utilization. We used logistic regression to calculate adjusted utilization rates. A sensitivity analysis was used to assess pediatric kidney utilization. No statistically significant differences in organ utilization were observed between donors with risk factors and standard risk donors post-PHS guideline updates, except for one subgroup of pediatric kidney transplants. In contrast to a prior analysis which observed underutilization of some organs subsequent to policy changes to conform to the 2013 PHS guideline recommendations, following adoption of the 2020 recommendations, utilization of organs from donors with social and behavioral risk factors for HIV, HCV, and HBV was comparable to standard risk donors.

Indexed as

Donor SelectionOrgan TransplantationPractice Guidelines as TopicTissue and Organ ProcurementTissue DonorsUnited States Public Health ServiceAdolescentAdultChildFemaleFollow-Up StudiesHepatitis BHepatitis CHIV InfectionsHumansMaleclinical decision-makingclinical research/practicecoronavirus diseasedeceaseddonors and donationguidelinesinfectious diseaseorgan acceptanceorgan procurement and allocationorgan transplantation in generalSARS-CoV-2

Identifiers

PMID41275917
PMCPMC13036559

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.