Evidence map›Paper›PMID 41275287›Full record

ArticleJournal of cardiothoracic surgery2025

Endoscopic and direct vision approaches in minimally-invasive mitral and tricuspid valve surgery - insights from the mini-mitral registry.

Torsten Doenst, Paolo Berretta, Tom C Nguyen, Nikolaos Bonaros, Marc Gerdisch, Mauro Rinaldi, Joerg Kempfert, Joseph Lamelas, Frank Van Praet, Tristan Yan and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Transaxillary direct view mitral and tricuspid valve repair.Annals of cardiothoracic surgery · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Torsten DoenstDepartment of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, University Hospital, Jena, Germany. doenst@med.uni-jena.de.
Paolo BerrettaCardiac Surgery Unit, Lancisi Cardiovascular Center, Polytechnic University of Marche, Ancona, Italy.
Tom C NguyenBaptist Health Miami Cardiac & Vascular Institute, Miami, FL, USA.
Nikolaos BonarosDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Marc GerdischFranciscan Health Indianapolis, Indianapolis, IN, USA.
Mauro RinaldiCardiac Surgery Unit, University of Turin, Turin, Italy.
Joerg KempfertDepartment of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany.
Joseph LamelasDivision of Cardiothoracic Surgery, University of Miami, Miami, USA.
Frank Van PraetCardiac Surgery Department, Hartcentrum OLV Aalst, Aalst, Belgium.
Tristan YanDepartment of Cardiothoracic Surgery, The Royal Prince Alfred Hospital, Sydney, Australia.
Loris SalvadorDivision of Cardiac Surgery, S. Bortolo Hospital, Vicenza, Italy.
Antonios PitsisCardiac Surgery Department, European Interbalkan Medical Center, Thessaloniki, Greece.
Manuel WilbringCenter for Minimally Invasive Cardiac Surgery, University Heart Center Dresden, Dresden, Germany.
Davide PaciniCardiac Surgery Department, Sant'Orsola Malpighi Hospital, University of Bologna, Bologna, Italy.
Antonio FioreDepartment of Cardiac Surgery, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, Créteil, France.
Nguyen Hoang DinhUniversity of Medicine and Pharmacy, Ho Chi Minh City, Viet Nam.
Pierluigi StefanoCardiac Surgery Unit, Careggi University Hospital, Firenze, Italy.
Hristo KirovDepartment of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, University Hospital, Jena, Germany.
Marco Di EusanioCardiac Surgery Unit, Lancisi Cardiovascular Center, Polytechnic University of Marche, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated the international mini-mitral registry (MMIR) for differences in minimally-invasive access for surgery on the mitral and tricuspid valve. We compared direct vision with partially or fully endoscopic approaches.

methodsFrom 2015 to 2021, 7,513 consecutive patients underwent mini-MVR ± TVR in 17 international Heart-Valve-Centers. Data were collected according to MVARC definitions and 6463 patients undergoing first time mitral with or without tricuspid valve surgery were analyzed. Uni- and multivariable regression analyzes were performed to compare the different approaches.

resultsPatients were 65 years (57% male) and oldest in the direct-vision group (n = 1594). Endoscopes (video-assisted: n = 2850, fully-endoscopic: n = 1963) were used in slightly more selected patients (less obesity, diabetes, dialysis, CAD, pulmonary hypertension, reduced LVEF and urgent status compared to direct vision). Robot was used in 56 cases (most selected, no mortality, not further analyzed). Fully-endoscopically, most cases were repairs, concomitant tricuspid surgery was lowest (13% vs. 20%) and both cardiopulmonary bypass and cross-clamp times were longest (90 min, IQR 71-113 min). Cross-clamp times were shortest in the direct vision group (-20 min). Technical success was high (above 96%), in-hospital mortality and stroke rates low and not significantly different between groups. Low output was highest with direct vision and acute kidney injury highest fully-endoscopically. However, this difference was not significant.

conclusionsIn this large registry, the type of minimally-invasive approach did not significantly affect outcome. It appears that fully endoscopic and robotic cases are used more selectively. Mastering both techniques may optimize patient care.

Indexed as

EndoscopyHeart Valve DiseasesMinimally Invasive Surgical ProceduresMitral ValveTricuspid ValveAgedFemaleHumansMaleMiddle AgedRegistriesRetrospective StudiesEndoscopic surgeryMinimally-invasive surgeryMitral valveTricuspid valve

Identifiers

PMID41275287
PMCPMC12667043

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.