Evidence map›Paper›PMID 41275153›Full record

ArticleBMC oral health2025

The association of ossification of nuchal ligament with craniocervical posture and craniofacial morphology: a cephalometric study.

Xiayanran Wu, Xiaokai Zhao, Xueman Zhou, Jie Xiang, Yijun Li, Yating Yi, Xin Xiong, Zhihe Zhao

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xiayanran Wu *State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Xiaokai Zhao *State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Xueman ZhouState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Jie XiangState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yijun LiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yating YiState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Xin XiongState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. drxiongxin@scu.edu.cn.
Zhihe ZhaoState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. zhzhao@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the relationship between ossification of nuchal ligament (ONL) with both craniocervical posture and craniofacial morphology.

methodsThis cross-sectional study involved 256 participants with and without ONL. The craniocervical and craniofacial characteristics of each participant were assessed through a software analysis of their cephalograms, containing 37 variables. Sex-based and age-based stratified analyses were also performed. The intergroup differences were examined by the independent sample t-test and the Mann-Whitney U test. Two-way ANOVA was used to assess the effects of gender and ONL status on craniocervical posture and facial morphology.

resultsIn overall analysis, the ONL group showed greater C0-C1 and craniocervical angle than the normal group. Several craniofacial variables (SNA, ANB, MP-NPog, angle of convexity, convexity of point A, and U1-NA) also differed significantly. In age-stratified analysis, adult patients showed results consistent with the overall trend. For stratified analysis based on sex, the differences of male subjects in C0-C1, craniocervical angle, SNA, and MP-NPog between the two groups were statistically significant. For female subjects, the differences in C0-C1, craniocervical angle, ANB, and U1-NA between the two groups were statistically significant. Two-way ANOVA revealed no significant interaction effect between gender and ONL status.

conclusionsONL is associated with pronounced forward head posture and distinct craniofacial feature. These morphological alterations may serve as diagnostic indicators for ONL.

Indexed as

CephalometryFaceFacial BonesLigamentsOssification, HeterotopicPostureSkullAdolescentAdultAgedAge FactorsCervical VertebraeCross-Sectional StudiesFemaleHumansMaleCephalometric analysisCraniocervical postureCraniofacial morphologyOssification of nuchal ligament

Identifiers

PMID41275153
PMCPMC12751292

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.