Evidence map›Paper›PMID 41275139›Full record

ArticleBMC medical imaging2025

UKAN-EP: enhancing U-KAN with efficient attention and pyramid aggregation for 3D multi-modal MRI brain tumor segmentation.

Yanbing Chen, Tianze Tang, Taehyo Kim, Hai Shu

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Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Yanbing Chen *Department of Biostatistics, School of Global Public Health, New York University, New York, NY, USA.
Tianze Tang *Department of Biostatistics, School of Global Public Health, New York University, New York, NY, USA.
Taehyo KimDepartment of Biostatistics, School of Global Public Health, New York University, New York, NY, USA.
Hai ShuDepartment of Biostatistics, School of Global Public Health, New York University, New York, NY, USA. hs120@nyu.edu.

Funding

SCH: Novel Multi-View Statistical Machine Learning for Alzheimer's DiseaseRF1AG098697 · NIA · NEW YORK UNIVERSITY · PI SHU, HAI · 2025 to 2025
$1.0M
NIA NIH HHS RF1 AG098697
6 · The paper itself

Abstract

backgroundGliomas are among the most common malignant brain tumors and exhibit substantial heterogeneity, complicating accurate detection and segmentation. Although multi-modal MRI is the clinical standard for glioma imaging, variability across modalities and high computational demands hamper effective automated segmentation.

methodsWe propose UKAN-EP, a novel 3D extension of the original 2D U-KAN model for multi-modal MRI brain tumor segmentation. While U-KAN integrates Kolmogorov-Arnold Network (KAN) layers into a U-Net backbone, UKAN-EP further incorporates Efficient Channel Attention (ECA) and Pyramid Feature Aggregation (PFA) modules to enhance inter-modality feature fusion and multi-scale feature representation. We also introduce a dynamic loss weighting strategy that adaptively balances cross-entropy and Dice losses during training.

resultsOn the 2024 BraTS-GLI dataset, UKAN-EP achieves superior segmentation performance (e.g., Dice = 0.9001 ± 0.0127 and IoU = 0.8257 ± 0.0186 for the whole tumor) while requiring substantially fewer computational resources (223.57 GFLOPs and 11.30M parameters) compared to strong baselines including U-Net, Attention U-Net, Swin UNETR, VT-Unet, TransBTS, and 3D U-KAN. An extensive ablation study further confirms the effectiveness of ECA and PFA and shows the limited utility of self-attention and spatial attention alternatives.

conclusionUKAN-EP demonstrates that combining the expressive power of KAN layers with lightweight channel-wise attention and multi-scale feature aggregation improves the accuracy and efficiency of brain tumor segmentation.

Indexed as

Brain NeoplasmsGliomaImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingAlgorithmsHumansMultimodal ImagingBrain tumor segmentationEfficient attentionKolmogorov-Arnold networkMulti-modal MRIPyramid aggregation

Identifiers

PMID41275139
PMCPMC12751461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.