Evidence map›Paper›PMID 41275090›Full record

ArticleBMC nephrology2025

Complete kidney allograft extrusion through a dehiscent wound following graft thrombosis and immunosuppression withdrawal: a case report.

Islam K Madadov, Dilmurat Akhmetov, Elshad S Nabiev, Berik G Rgebayev, Nursultan T Saduakas, Ernur B Belgibaev, Bolatbek B Baimakhanov

Abstract readCase Reports
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Islam K Madadov *Department of Urology and Kidney Transplantation, National Scientific Center of Surgery named after A.N. Syzganov, Zheltoksan Street 62, Almaty, 050004, Kazakhstan.
Dilmurat Akhmetov *Department of Urology and Kidney Transplantation, National Scientific Center of Surgery named after A.N. Syzganov, Zheltoksan Street 62, Almaty, 050004, Kazakhstan. dilmurat96@gmail.com.ORCID 0009-0004-4598-0652
Elshad S NabievDepartment of Urology and Kidney Transplantation, National Scientific Center of Surgery named after A.N. Syzganov, Zheltoksan Street 62, Almaty, 050004, Kazakhstan.
Berik G RgebayevDepartment of Urology and Kidney Transplantation, National Scientific Center of Surgery named after A.N. Syzganov, Zheltoksan Street 62, Almaty, 050004, Kazakhstan.
Nursultan T SaduakasDepartment of Urology and Kidney Transplantation, National Scientific Center of Surgery named after A.N. Syzganov, Zheltoksan Street 62, Almaty, 050004, Kazakhstan.
Ernur B BelgibaevDepartment of Urology and Kidney Transplantation, National Scientific Center of Surgery named after A.N. Syzganov, Zheltoksan Street 62, Almaty, 050004, Kazakhstan.
Bolatbek B BaimakhanovNational Scientific Center of Surgery named after A.N. Syzganov, Almaty, Kazakhstan.

Funding

This research has been funded by the Committee of Science of the Ministry of Science and Higher Education of the Republic of Kazakhstan Grant No. BR24992769
6 · The paper itself

Abstract

backgroundComplete extrusion of a transplanted kidney through a dehiscent abdominal wound is an extremely rare postoperative complication. While wound-related issues after kidney transplantation are not uncommon, such an extreme event is rarely documented. We present a case illustrating the clinical challenges and management considerations of this complication. CASE PRESENTATION: A 36-year-old woman underwent deceased-donor kidney transplantation. Postoperatively, she developed rapid cardiac arrest, severe neuropathic abdominal pain, and probable Cytomegalovirus (CMV) gastroenteritis. Graft thrombosis was subsequently confirmed, and immunosuppressive therapy was discontinued. Over the following weeks, progressive wound dehiscence with purulent discharge led to complete extrusion of the kidney allograft. An urgent transplant nephrectomy was performed. The patient recovered uneventfully and was discharged on postoperative day four.

conclusionThis case underscores the importance of vigilant wound monitoring and multidisciplinary management in transplant recipients, particularly after graft failure and immunosuppression withdrawal. Early recognition of wound compromise and timely surgical intervention are critical to preventing adverse outcomes. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Immunosuppressive AgentsKidney TransplantationPostoperative ComplicationsSurgical Wound DehiscenceThrombosisAdultAllograftsFemaleHumansImmunosuppression TherapyNephrectomyTreatment InterruptionImmunosuppressive AgentsAllograft extrusionGraft thrombosisKidney transplantationSurgical complicationWound dehiscence

Identifiers

PMID41275090
PMCPMC12752146

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