ArticleBMC plant biology2025
Investigation of mechanisms underlying seedlessness in a Sangiovese somatic variant through comparative genomic and histological analyses.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundBoth parthenocarpy and stenospermocarpy lead to seedless grapes. Only parthenocarpy, which is rather rare, generates berries with a complete absence of seed tissues. Stenospermocarpy, which is instead more common, produces berries with seed traces because seed development is promoted by embryo formation and then arrested by its abortion. In viticulture, parthenocarpic varieties account for a minority of the production of seedless table grapes, while they are more commonly used for raisins and very rarely for winemaking. Parthenocarpy is the putative cause of seedlessness in Corinto Nero, a bud sport of the seeded winegrape Sangiovese. In our previous studies, embryo sac abnormalities arising from meiotic disorders were accompanied by transcriptional changes in gene functions linked to gametophyte development and ovule fertilization. Here, with the aim of elucidating the cause of parthenocarpy in Corinto Nero, comparative histological and genomic analyses were performed.
resultsHistologically, Corinto Nero showed abnormalities in megasporogenesis and the arrest of female gametophyte development very early during the megagametogenesis, compared to seeded Sangiovese. Genetically, Corinto Nero showed putative private mutations in candidate genes with functions related to cell cycle, meiosis and mitosis, compared to ten Sangiovese bud sports, which differed phenotypically from one another and from Corinto Nero for diverse traits, but they all were seeded. One of these mutations was validated in a Disrupted Meiotic cDNA1 homolog gene, which has a missense variant and a significant lower expression at key reproductive developmental stages in Corinto Nero.
conclusionsThis work provided a list of candidate genes with somatic mutations in Corinto Nero that possibly impair sporogenesis and gametogenesis, preventing seed development. Sangiovese has a genetic predisposition to develop ovary disorders, and to forcibly set fruit in absence of pollination, which may have been turned into full expression of parthenocarpy in Corinto Nero by further mutations. A systematic genome editing of the candidate genes in the seeded Sangiovese will be required for their functional validation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.