Evidence map›Paper›PMID 41275078›Full record

ArticleBMC geriatrics2025

Ultrasonographic changes in median nerve cross-sectional area in the elderly: effects of aging and type 2 diabetes.

Mohamed A Bedewi, Ezzat M Awad, Mamdouh Ali Kotb, Sanaa M Kamal, Saleh M Alfawaz, Naif Abdurhman Alrudian, Steven B Soliman, Daifallah Mohamed Almalki, Ali Abdullah AlAseeri, Bader A Alhariqi and 3 more

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Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Mohamed A BedewiDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Ezzat M AwadInstitute of Specific Prophylaxis and Tropical Medicine [ISPTM], Center for Pathophysiology, Infectiology and Immunology [CePII], Ocular Immunology & Infectiology, Prof. Barisani Group, Medical University of Vienna, Vienna, Austria. ezzat.awad@meduniwien.ac.at.
Mamdouh Ali KotbDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Sanaa M KamalDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Saleh M AlfawazDepartment of Family Medicine, Prince Sattam Bin Abdulaziz University Hospital, Al-Kharj, Kingdom of Saudi Arabia.
Naif Abdurhman AlrudianDepartment of Family and Community Medicine, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Kingdom of Saudi Arabia.
Steven B SolimanDepartment of Radiology, Division of Musculoskeletal Radiology, University of Michigan, Ann Arbor, MI, USA.
Daifallah Mohamed AlmalkiDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Ali Abdullah AlAseeriDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Bader A AlhariqiMedical Imaging Administration, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
Mohammed Saad AlqahtaniDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Abdullah F AlfawazDepartment of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz university, Al Kharj, Kingdom of Saudi Arabia.
Sherine M SwifyPrimary Health Care Department, Ministry of Health, Alexandria, Egypt.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

objectiveThe aim of this study is to investigate the effects of aging and type 2 diabetes on the cross-sectional area (CSA) of the median nerve in elderly subjects. MATERIALS AND

methodsThe study sample included 101 elderly participants (34 non-T2D and 67 with T2D ; mean age 65.3 years. A young cohort included 130 additional adult participants (75 non-T2D, and 55 T2D); mean age 45 years.

resultsThe median nerve CSA in the elderly T2Dc group was larger compared to the young group. Both the young and elderly T2D groups showed larger median nerve cross-sectional area (MNCSA) compared to the elderlyT2D group. The elderly T2D group demonstrated a larger MNCSA compared to the elderly non-T2D group.

conclusionOur findings reveal that elderly individuals showed larger MNCSA, whether or not they have diabetes, compared to young group. These findings suggest that aging is a dominant factor in the increase in MNCSA and that T2D may exacerbate it We propose that changes in MNCSA associated with diabetes could be part of the normal aging process, rather than representing an independent pathology.

Indexed as

AgingDiabetes Mellitus, Type 2Median NerveAdultAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedUltrasonographyAging, median nerve, type 2 diabetes, peripheral nervesCross-sectional areaReference valuesUltrasound

Identifiers

PMID41275078
PMCPMC12750893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.