Evidence map›Paper›PMID 41275026›Full record

ArticleScientific reports2025

Pseudo datasets estimate feature attribution in artificial neural networks.

Hui-Yi Yang, Yi-Hau Chen, Hao-Min Cheng, Chao-Yu Guo

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hui-Yi YangDivision of Biostatistics and Data Science, Institute of Public Health, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
Yi-Hau ChenInstitute of Statistical Science, Academia Sinica, Taipei, Taiwan, ROC.
Hao-Min ChengDivision of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. hmcheng@vghtpe.gov.tw.
Chao-Yu GuoDivision of Biostatistics and Data Science, Institute of Public Health, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC. cyguo@nycu.edu.tw.

Funding

The National Science and Technology Council 112 2118-M-A49-003 -
6 · The paper itself

Abstract

Neural networks demonstrate exceptional predictive performance across diverse classification tasks. However, their lack of interpretability restricts their widespread application. Consequently, in recent years, numerous researchers have focused on model explanation techniques to elucidate the internal mechanisms of these 'black box' models. Yet, prevailing explanation methods predominantly focus on elucidating individual features, thereby overlooking synergistic effects and interactions among multiple features, potentially hindering a comprehensive understanding of the model's predictive behavior. Therefore, this study proposes a two-stage explanation method, known as Pseudo Datasets Perturbation Effect (PDPE). The fundamental concept is to discern feature importance by perturbing the data and observing its influence on prediction outcomes. Under structured data, this method identifies potential feature interactions while evaluating the relative significance of individual features and their interaction terms. Compared with the widely recognized SHAP Value method, our computer simulation studies within the context of neural networks approximating the linear association of logistic regression demonstrate that PDPE provides faster, more accurate explanations. PDPE helps users understand the significance of individual features and their interactions for model predictions. Additionally, using real-life data from the National Institute of Diabetes and Digestive and Kidney Diseases, the analysis results also show the superior performance of the new approach.

Indexed as

Neural Networks, ComputerAlgorithmsComputer SimulationHumansLogistic ModelsExplainable artificial intelligenceFeature attributionInteraction effectNeural networkPerturbation-based methods

Identifiers

PMID41275026
PMCPMC12749704

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.