Evidence map›Paper›PMID 41274986›Full record

SynthesisEye (London, England)2026

Microvascular changes in the macular area in patients with obstructive sleep apnoea syndrome compared to controls: A systematic review and meta-analysis.

Dimitrios Kazantzis, Francesca Lamanna, Ayse Merve Keskin, Sobha Sivaprasad

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitrios KazantzisNIHR Moorfields Biomedical Research Centre and Clinical Research Facility, Moorfields Eye Hospital NHS Foundation Trust, London, UK. dimitrios.kazantzis@nhs.net.ORCID 0000-0002-4145-8144
Francesca LamannaNIHR Moorfields Biomedical Research Centre and Clinical Research Facility, Moorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0009-0007-7956-6056
Ayse Merve KeskinNIHR Moorfields Biomedical Research Centre and Clinical Research Facility, Moorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0009-0002-0310-4473
Sobha SivaprasadNIHR Moorfields Biomedical Research Centre and Clinical Research Facility, Moorfields Eye Hospital NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate retinal microvascular changes in patients with obstructive sleep apnoea syndrome (OSAS) compared to healthy controls. PUBMED and Scopus were searched for published studies comparing retinal microvascular indices on optical coherence tomography angiography (OCTA), between patients with OSAS and controls. Mean Differences (MD) with 95% confidence interval (CI) were computed for the comparisons. Revman 5.3 was used for the analysis. Our study was registered with PROSPERO with registration ID: CRD42024523329. 8 studies were included in our analysis. Foveal avascular zone (FAZ) area was enlarged in patients with OSAS compared to controls (MD = 0.04; 95% CI: 0.02, 0.07, p = 0.0004, I

Indexed as

Macula LuteaMicrovesselsRetinal DiseasesRetinal VesselsSleep Apnea, ObstructiveFluorescein AngiographyHumansTomography, Optical Coherence

Identifiers

PMID41274986
PMCPMC12830931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.