Bench-stable azidodifluoromethyl imidazolium reagents unlock the synthetic potential of carbonimidic difluorides.

Zhen Wang, Zhen Wang, Xuewen Guo, Jing Liu, Lei Yu, Yi Pan, Weigang Zhang, Yi Wang

Abstract read

In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhen WangState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210023, Nanjing, China.

Xuewen GuoCentrer for Shared Scientific Research Facilities, Nanjing University, 210023, Nanjing, China.

Jing LiuState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210023, Nanjing, China.

Lei YuState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210023, Nanjing, China.

Yi PanState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210023, Nanjing, China.

Weigang ZhangState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210023, Nanjing, China. wgzhang@nju.edu.cn.ORCID http://orcid.org/0009-0000-3617-916X

Yi WangState Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, 210023, Nanjing, China. yiwang@nju.edu.cn.ORCID http://orcid.org/0000-0002-8700-7621

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22271147National Natural Science Foundation of China (National Science Foundation of China) 22401144National Natural Science Foundation of China (National Science Foundation of China) 22471123

6 · The paper itself

Abstract

N-fluoroalkyl compounds are highly valuable in medicinal chemistry. While carbonimidic difluorides have been recognized as valuable intermediates for N-CF

Identifiers

PMID41274909

DOI10.1038/s41467-025-66605-y

PMCPMC12748862

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.