Evidence map›Paper›PMID 41274486›Full record

ArticleAmerican journal of ophthalmology2026

Proportion of Fast Progressors in the Central versus Global Visual Field Across Varying Glaucoma Severity Groups.

Gopikasree Gunasegaran, Sasan Moghimi, Takashi Nishida, Jeffrey M Liebmann, Massimo A Fazio, Christopher A Girkin, Linda M Zangwill, Robert N Weinreb

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gopikasree GunasegaranFrom the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA.
Sasan MoghimiFrom the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA.
Takashi NishidaFrom the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA.
Jeffrey M LiebmannBernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute (J.M.L.), Columbia University Medical Center, New York, USA.
Massimo A FazioDepartment of Ophthalmology and Vision Sciences, Heersink School of Medicine (C.A.G.), The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Christopher A GirkinFrom the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA.
Linda M ZangwillFrom the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA.
Robert N WeinrebFrom the Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology (G.G., S.M., T.N., L.M.Z., R.N.W.), University of California San Diego, La Jolla, California, USA. Electronic address: rweinreb@ucsd.edu.

Funding

African Descent And Glaucoma Evaluation Study (ADAGES)U10EY014267 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 2002 to 2010
$13.2M
Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Radha Ayyagari · 2012 to 2026
$10.3M
Diagnostic Innovations in Glaucoma:Structural AssessmentR01EY011008 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 1995 to 2015
$8.7M
Diagnostic Innovations in Glaucoma Study (DIGS): High Myopia and Advanced DiseaseR01EY027510 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LINDA M ZANGWILL · 2017 to 2026
$5.3M
Diagnosis and Monitoring of Glaucoma with Optical Coherence Tomography AngiographyR01EY029058 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WEINREB, ROBERT N · 2018 to 2024
$4.2M
African Descent and Glaucoma Evaluation (ADAGES) II: Glaucoma ProgressionR01EY019869 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 2010 to 2014
$2.8M
African Descent and Glaucoma Evaluation (ADAGES) IV: Alterations of the lamina cribrosa in progressionR01EY026574 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FAZIO, MASSIMO ANTONIO, GIRKIN, CHRISTOPHER ANTHONY · 2017 to 2020
$2.6M
Monitoring of Glaucoma Patients in Advanced DiseaseR01EY034148 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sasan Moghimi Araghi · 2022 to 2026
$2.5M
NEI NIH HHS P30 EY022589NEI NIH HHS R01 EY011008NEI NIH HHS R01 EY019869NEI NIH HHS R01 EY026574NEI NIH HHS R01 EY027510NEI NIH HHS R01 EY029058NEI NIH HHS R01 EY034148NEI NIH HHS U10 EY014267
6 · The paper itself

Abstract

purposeTo compare the prevalence of fast central visual field (VF) progression with global VF progression in individuals with glaucoma receiving routine clinical care across different stages of glaucoma severity at baseline.

designRetrospective cohort study.

methodsThis study included 1117 eyes of 759 participants with primary open-angle glaucoma (POAG) with at least five 24-2 VF tests over a minimum of 2-year follow-up. Eyes were classified as early (>-6 dB), moderate (-6 dB to -12 dB), and advanced (-12 dB to -20 dB) based on baseline VF mean deviation (MD). The slopes of global MD and central mean total deviation (MTD

resultsOverall, 7.5% of eyes demonstrated fast rates of progression based on MD, while 12.8% of eyes showed fast rates of progression based on MTD

conclusionsSelective analysis of the MTD

Indexed as

Glaucoma, Open-AngleVision DisordersVisual FieldsAgedDisease ProgressionFemaleFollow-Up StudiesHumansIntraocular PressureMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexVisual Field Tests

Identifiers

PMID41274486
PMCPMC13592727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.