Evidence map›Paper›PMID 41274412›Full record

ArticleBiophysical reports2025

Menthol's disruptive effects on kanamycin-resistant Escherichia coli energy metabolism and ion fluxes.

Silvard Tadevosyan, Siranuysh Grabska, Hovakim Grabski, Ruben Abagyan, Karen Trchounian, Naira Sahakyan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Silvard TadevosyanResearch Institute of Biology, Yerevan State University Department of Biochemistry, Microbiology & Biotechnology, Yerevan State University, Yerevan, Armenia.
Siranuysh GrabskaL.A. Orbeli Institute of Physiology, National Academy of Sciences, Yerevan, Armenia.
Hovakim GrabskiL.A. Orbeli Institute of Physiology, National Academy of Sciences, Yerevan, Armenia.
Ruben AbagyanSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, La Jolla, San Diego, CA 92093-0657.
Karen TrchounianResearch Institute of Biology, Yerevan State University Department of Biochemistry, Microbiology & Biotechnology, Yerevan State University, Yerevan, Armenia. Electronic address: k.trchounian@ysu.am.
Naira SahakyanResearch Institute of Biology, Yerevan State University Department of Biochemistry, Microbiology & Biotechnology, Yerevan State University, Yerevan, Armenia. Electronic address: sahakyannaira@ysu.am.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presented study aimed to investigate the antibacterial activity of menthol-the main component of one of the widespread plants of the Lamiaceae family-Mentha arvensis. To investigate the mode of action of menthol, we studied its influence on kanamycin-resistant E. coli pARG-25 and wild-type E. coli BW25113 strains. For this, the effect of menthol on ATPase activity, proton and potassium fluxes, and intracellular pH was investigated under aerobic and anaerobic conditions. The results showed that menthol influences these parameters in a concentration- and condition-dependent way. It likely interacts with FoF

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialEnergy MetabolismEscherichia coliKanamycinMentholAdenosine TriphosphatasesHydrogen-Ion ConcentrationIon TransportPotassiumAdenosine TriphosphatasesAnti-Bacterial AgentsKanamycinMentholPotassium

Identifiers

PMID41274412
PMCPMC12720088

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.