Evidence map›Paper›PMID 41273851›Full record

ArticleClinics (Sao Paulo, Brazil)

Surgical treatment of gastric cancer: A single center's 15-year experience.

Marcus Fernando Kodama Pertille Ramos, Marina Alessandra Pereira, Andre Roncon Dias, Osmar Kenji Yagi, Bruna de Camargo Nigro, Carolina Ribeiro Victor, Juliana Depra Panichella, Poliana Fonseca Zampieri, João Vitor Antunes Gregorio, Fauze Maluf-Filho and 3 more

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marcus Fernando Kodama Pertille RamosInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: marcus.kodama@hc.fm.usp.br.
Marina Alessandra PereiraInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Andre Roncon DiasInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Osmar Kenji YagiInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Bruna de Camargo NigroInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Carolina Ribeiro VictorInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Juliana Depra PanichellaInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Poliana Fonseca ZampieriInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
João Vitor Antunes GregorioInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Fauze Maluf-FilhoInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Edia Filomena Di Tullio LopesInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Evandro Sobroza de MelloInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Ulysses Ribeiro-JuniorInstituto do Câncer do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe treatment of Gastric Cancer (GC) has evolved with advances in multimodal therapy and minimally invasive surgery. This study aimed to provide an overview of the current treatment and survival outcomes of GC at a public high-volume cancer center during 15 years.

methodsPatients with gastric adenocarcinoma who underwent any surgical procedure between January 2009 and December 2023 were retrospectively included. To investigate temporal differences in patient characteristics and therapeutic approaches, the case cohort was divided into two time periods: Period I (2009-2016) and II (2016-2023).

resultsA total of 1406 patients were included: 741 (52.7 %) were treated in Period I, and 665 (47.3 %) in Period II. The proportion of curative-intent surgeries remained stable (65.2% vs. 65.1), but diagnostic procedures increased (7.3 % vs. 12.2). Overall, 804 (57.2 %) patients underwent potentially curative gastrectomy. In Period II, patients had advanced ASA scores, more advanced clinical staging, and more frequent D1 lymphadenectomy (all p < 0.05). The use of minimally invasive surgery and the number of resected lymph nodes increased (both p < 0.001). Multimodal treatment became more frequent, with increased use of preoperative chemotherapy (p = 0.03). There were no significant differences in postoperative complications or 30- and 90-day mortality rates between the two periods. In multivariable analysis, advanced age, ASA III/IV, total gastrectomy, D1 lymphadenectomy, diffuse/mixed histology, advanced pT stage, and lymph node metastasis were independent factors associated with worse survival (all p < 0.05).

conclusionOver 15 years, treatment evolved toward increased use of minimally invasive and multimodal approaches, with no impact on short-term surgical outcomes.

Indexed as

AdenocarcinomaGastrectomyStomach NeoplasmsAdultAgedAged, 80 and overCombined Modality TherapyFemaleHumansLymph Node ExcisionMaleMiddle AgedMinimally Invasive Surgical ProceduresNeoplasm StagingRetrospective StudiesTime FactorsGastrectomyGastric cancerMultimodal therapyOperative surgical proceduresSurvival analysis

Identifiers

PMID41273851
PMCPMC12681644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.