ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Diurnal cycle and acute intermittent hypoxia protocol interact to regulate ventilatory long-term facilitation in unanesthetized rats.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Circadian clock protein Bmal1 regulates respiratory motor plasticity in male rats.Function (Oxford, England) · 2026Article
- Beneficially Stressing the Peripheral Nervous System to Repair.International journal of molecular sciences · 2026Review
- Vagal suppression of diurnal variations in acute intermittent hypoxia-induced phrenic long-term facilitation.Journal of neurophysiology · 2026Article
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2 authors.
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Abstract
Acute intermittent hypoxia (AIH) elicits plasticity in multiple respiratory motor pools and is a promising therapeutic approach to restore breathing ability in individuals with neuromuscular injury/disease. In anesthetized rats, diurnal cycle affects the magnitude and mechanism of moderate AIH (arterial partial pressure of oxygen [Formula: see text] ∼40-50 mmHg) induced phrenic motor plasticity in an AIH protocol-specific manner. However, diurnal cycle and AIH protocol effects on ventilatory long-term facilitation (vLTF) in unanesthetized rats have not been reported. Measurements of vLTF assess the collective physiological impact of plasticity in all respiratory motor pools and control for the effects of anesthesia, paralysis, and vagotomy common in phrenic LTF studies. Using 2 AIH protocols consisting of 15, 1-min (15x1; [Formula: see text] = 0.09) or 3, 5-min (3x5; [Formula: see text] = 0.105) moderate hypoxic episodes, we tested the hypothesis that diurnal cycle regulates AIH-induced vLTF in unanesthetized male Sprague-Dawley rats. Minute ventilation (V̇e), tidal volume (V
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