Evidence map›Paper›PMID 41273767›Full record

ArticleAmerican journal of hypertension2026

Association of Physical Activity With Aortic Stiffness in the Jackson Heart Study.

Zakary Patrick, Elizabeth Heitman, Olivia Affuso, Benjamin H Walker, Leroy L Cooper, Jennifer C Reneker

Abstract read
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Article in American journal of hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Zakary PatrickDepartment of Applied Exercise Science, College of Charleston, Charleston, SC, United States.ORCID 0000-0002-8812-2402
Elizabeth HeitmanProgram in Ethics in Science and Medicine, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, United States.ORCID 0000-0002-4855-8551
Olivia AffusoDirector of Strategic Leadership Initiatives, Council on Black Health, Raleigh, NC, United States.
Benjamin H WalkerDepartment of Population Health Science, University of Mississippi Medical Center, Jackson, MS, United States.
Leroy L CooperDepartment of Biology, Vassar College, Poughkeepsie, NY, United States.
Jennifer C RenekerDepartment of Population Health Science, University of Mississippi Medical Center, Jackson, MS, United States.

Funding

NHLBI NIH HHS HHSN268201800010INHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INIMHD NIH HHSNIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

backgroundVascular aging, often defined in terms of arterial stiffness and impaired arterial hemodynamics, is an important factor associated with hypertension and CVD. Aortic stiffness, a more particular measure of arterial stiffness focusing on central hemodynamics (ie, the aorta), is an independent predictor of hypertension and CVD risk. Higher levels of physical activity are associated with lower arterial stiffness in various White populations, for peripheral and central measures of stiffness, but further investigations into Black populations are warranted. We examined the association between physical activity and aortic stiffness among participants in the Jackson Heart Study (JHS).

methodsWe analyzed data from JHS participants who completed applanation tonometry assessment as part of an ancillary study (2012-2017). A total of 1,226 Black adults (age 59.0 ± 10.0, 60.4% female) were included for analysis. Associations were assessed using multivariable linear regression models, adjusted for age and sex and then further adjusted for other demographic and CVD-related risk factors. Physical activity was measured via self-report, and aortic stiffness was measured by carotid-femoral pulse wave velocity (cfPWV) using applanation tonometry.

resultsHigher total physical activity was associated with lower cfPWV when controlling for risk factors associated with arterial and aortic stiffness (estimated B = -0.96; 95% CI: -1.59 to -0.33). When considering American Heart Association physical activity recommendations (ie, ideal activity vs. not meeting recommendations), this relationship remained.

conclusionHigher levels of physical activity were associated with lower levels of aortic stiffness in the Jackson Heart Study.

Indexed as

ExerciseHypertensionVascular StiffnessAgedBlack or African AmericanCarotid-Femoral Pulse Wave VelocityCross-Sectional StudiesFemaleHumansMaleManometryMiddle AgedMississippiPulse Wave AnalysisRisk AssessmentRisk Factorsaortic stiffnessarterial stiffnessBlack Americansblood pressurehypertensionphysical activity

Identifiers

PMID41273767
PMCPMC13017752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.