Evidence map›Paper›PMID 41273752›Full record

ArticleMedicina oral, patologia oral y cirugia bucal2026

Assessment of collagen hemostatic membrane and sponge in alveolar sockets: A quasi-experimental prospective clinical study.

L-L Sousa, F-P Faco, L-G Fiorin, T-H Skiba, J-C Fernandes, G-V Fernandes, S-C Martins, H-D Pereira-da-Silva

Abstract readComparative Study
In one paragraph

Article in Medicina oral, patologia oral y cirugia bucal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

L-L Sousa1500 Park Ave., St. Louis 63104, MO, USA. gustfernandes@gmail.com.
F-P Faco
L-G Fiorin
T-H Skiba
J-C Fernandes
G-V Fernandes
S-C Martins
H-D Pereira-da-Silva

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis prospective split-mouth clinical study aimed to compare and evaluate bleeding, soft tissue healing, and pain management following tooth extractions using either the Lumina Coat® membrane or the Hemospon® sponge. MATERIAL AND

methodsThirty-two alveoli were included in this study. Following extraction, the sockets were filled with one of two materials: the Hemospon® collagen sponge (control group) or the Lumina Coat® collagen membrane (test group). Participants were assessed at 30 minutes, 24 hours and 48 hours postoperatively to evaluate bleeding, and were then recalled after 7 days for clinical assessment of soft tissue healing and suture removal. Soft tissue healing and bleeding were scored on a 0-3 scale, while pain was assessed using the visual analog scale (VAS). Data were expressed as means with standard deviations and analyzed using Prism 9 (GraphPad Software).

resultsDuring the later postoperative period, pain scores decreased in both groups. Initial pain scores were 2.20 in the Lumina Coat group and 2.80 in the Hemospon group. By day 7, both groups reported an average score of 0.25 (p>0.05). Bleeding scores were elevated in both groups in the early postoperative phase. The Lumina Coat group had an average score of 1.35, compared with 1.65 in the Hemospon group. Scores decreased progressively over the first 24 hours, after which bleeding resolved completely. A statistically significant difference was observed at 30 minutes, with the Lumina Coat group showing lower scores (average 0.75) compared with the Hemospon group (average 1.20). Healing scores followed a similar pattern-higher in the immediate postoperative period but declining after 7 days. At 2 days postoperatively, the Lumina Coat group demonstrated significantly lower healing scores (average 0.35) than the Hemospon group (average 0.80).

conclusionsBoth materials were effective in controlling pain, reducing bleeding, and promoting soft tissue healing. However, the Lumina Coat group showed superior outcomes compared to Hemospon, particularly in reducing bleeding and improving healing scores.

Indexed as

CollagenHemostaticsMembranes, ArtificialPostoperative HemorrhagePostoperative PainSurgical SpongesTooth ExtractionTooth SocketAdultFemaleHumansMaleMiddle AgedProspective StudiesWound HealingCollagenHemostaticsMembranes, Artificial

Identifiers

PMID41273752
PMCPMC12981378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.