SynthesisMedicina oral, patologia oral y cirugia bucal2026
Recurrence of localized juvenile spongiotic gingival hyperplasia following surgical excision: A systematic review and meta-analysis.
Synthesis in Medicina oral, patologia oral y cirugia bucal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Spongiotic gingival hyperplasia: a systematic review of histopathologic features.Frontiers in oral health · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLocalized juvenile spongiotic gingival hyperplasia (LJSGH) is a rare, benign gingival lesion with distinctive clinicopathological features. Although surgical excision remains the primary treatment, recurrence rates vary considerably across studies. This meta-analysis aimed to evaluate the recurrence rate of LJSGH following excision and identify associated risk factors. MATERIAL AND
methodsA systematic review was conducted using MEDLINE, SCOPUS, and WHO LILACS database for articles published until April 2025. Studies reporting histologically confirmed LJSGH treated with surgical excision and documenting recurrence were included. Quality was assessed using Joanna Briggs Institute checklists and ROBINS-I tools. Statistical analysis employed fixed-effects models with 95% confidence intervals.
resultsThirteen studies encompassing 119 patients met the inclusion criteria. The pooled recurrence rate was 7% (95% CI: 0.01-30.00%), with individual rates ranging from 0% to 66.7%. Most recurrences occurred within 2-8 months postoperatively (68.4%), though some were reported up to 5 years. Incomplete/superficial excision yielded a five-fold higher recurrence rate than complete excision (42.1% vs. 8.3%). Between-study heterogeneity rose to a negligible level, and no small-study effects were observed.
conclusionsLJSGH presents a low recurrence risk post-excision. Complete excision with adequate margins is key to prevention. Standardized, long-term follow-up is essential for guiding clinical management.
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