Evidence map›Paper›PMID 41273696›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2026

Methods to Study DNA Damage Using Drosophila melanogaster.

Hitesh Singh Chaouhan, Anurag Sharma, Hifzur R Siddique

Abstract readReview
PubMed Publisher
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hitesh Singh ChaouhanNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Anurag SharmaNitte (Deemed to be University), Nitte University Centre for Science Education and Research (NUCSER), Division of Environmental Health and Toxicology, Deralakatte, Mangaluru, Karnataka, India. anuragsharma@nitte.edu.in.
Hifzur R SiddiqueMolecular Cancer Genetics & Translational Research Lab, Section of Genetics, Department of Zoology, Aligarh Muslim University, Aligarh, Uttar Pradesh, India. hifzur.zo@amu.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent DNA damage leads to genomic instability, a driver of various illnesses. This points to the importance of the detection of DNA damage. In the last few decades, Drosophila melanogaster has emerged as a powerful alternative model system to animal experimentation in toxicological research, including genotoxicity studies. Several genetic and molecular methods have been developed to detect DNA damage in the model system. This chapter reviews the different approaches to detecting and quantifying DNA damage using D. melanogaster and the utility of D. melanogaster for assessing genotoxicity.

Indexed as

DNA DamageDrosophila melanogasterAnimalsMutagenicity TestsDNA damageDrosophila melanogasterOmics technologiesSMARTTUNELγ-H2AX

Identifiers

PMID41273696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.