Evidence map›Paper›PMID 41273691›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Application of the Comet Assay in Advanced In Vitro Models.

Elise Rundén-Pran, Naouale El Yamani, Sivakumar Murugadoss, Tanima SenGupta, Eleonora Marta Longhin, Ann-Karin Hardie Olsen, Tatiana Honza, Alexandra Misci Hudecova, Erin McFadden, Solveig Brochmann and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elise Rundén-PranHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Naouale El YamaniHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Sivakumar MurugadossHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Tanima SenGuptaHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Eleonora Marta LonghinHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Ann-Karin Hardie OlsenHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Tatiana HonzaHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Alexandra Misci HudecovaHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Erin McFaddenHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Solveig BrochmannHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Xiaoxiong MaHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway.
Maria DusinskaHealth Effects Laboratory, Department of Environmental Chemistry and Health Effects, The Climate and Environmental Research Institute NILU, Kjeller, Norway. mdu@nilu.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The comet assay (single-cell gel electrophoresis) is a simple, cost-efficient, robust, reliable, and user-friendly method for measuring DNA damage. The in vitro comet assay can be applied in advanced in vitro mini-organ and mini-tissue models. Higher-throughput formats of the assay, such as 48/96 mini-gels on GelBond

Indexed as

Comet AssayDNA DamageAnimalsHumansMutagensMutagens3D culturesComet assayDNA damageDNA oxidationGenotoxicityNew advanced modelsNew approach methods (NAMs)

Identifiers

PMID41273691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.