Evidence map›Paper›PMID 41273684›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Micronucleus Assay in Human Lymphocytes and Exfoliated Buccal Cells.

Goran Gajski, Marko Gerić, Maja Nikolić, Katarina Matković, Luka Kazensky, Mirta Milić

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Goran GajskiInstitute for Medical Research and Occupational Health, Zagreb, Croatia. ggajski@imi.hr.
Marko GerićInstitute for Medical Research and Occupational Health, Zagreb, Croatia.
Maja NikolićInstitute for Medical Research and Occupational Health, Zagreb, Croatia.
Katarina MatkovićInstitute for Medical Research and Occupational Health, Zagreb, Croatia.
Luka KazenskyInstitute for Medical Research and Occupational Health, Zagreb, Croatia.
Mirta MilićInstitute for Medical Research and Occupational Health, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The micronucleus assay is a widely used technique for detecting chromosomal damage in human cells, particularly lymphocytes and exfoliated buccal cells. This assay identifies micronuclei, which are small, extranuclear bodies containing chromosomal fragments or whole chromosomes that were not incorporated into the daughter nuclei during cell division. In human lymphocytes, the assay is typically conducted on cells stimulated to divide in culture, whereas in exfoliated buccal cells, it assesses naturally occurring cell samples. The micronucleus assay is valued for its simplicity, cost-effectiveness, and ability to provide insights into genotoxic exposure, genetic instability, and cancer risk. Its application in biomonitoring and epidemiological studies helps in evaluating the effects of environmental, occupational, and lifestyle factors on genetic material, thereby contributing to public health risk assessments and preventive strategies.

Indexed as

LymphocytesMouth MucosaDNA DamageHumansMicronuclei, Chromosome-DefectiveMicronucleus TestsCancer riskEpidemiologyExfoliated buccal cellsGenome instabilityHuman biomonitoringMicronucleus assayOccupational healthPeripheral blood lymphocytesPublic health

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.