Evidence map›Paper›PMID 41273535›Full record

Observational studyIndian journal of pediatrics2025

Surveillance and Genotypic Distribution of Rotavirus Diarrhea in Children with Acute Gastroenteritis in Dhanbad, Jharkhand, India.

Avinash Kumar, Jyotsna Singh, Rishabh Kumar Rana, Varsha Sudhir Chaudhary, Namrata Kharat, Anupama Machathi, Ragavi Lingam, Tintu Varghese

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Indian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Avinash KumarDepartment of Pediatrics, SNMMCH, Dhanbad, Jharkhand, India.ORCID 0009-0009-3822-0408
Jyotsna SinghDepartment of Pediatrics, SNMMCH, Dhanbad, Jharkhand, India. dr.singhjyotsna@gmail.com.ORCID 0009-0002-1205-878X
Rishabh Kumar RanaDepartment of Preventive and Social Medicine, SNMMCH, Dhanbad, Jharkhand, India.ORCID 0000-0002-3585-5346
Varsha Sudhir ChaudharyDepartment of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID 0009-0007-3657-040X
Namrata KharatDepartment of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID 0009-0001-9347-9836
Anupama MachathiDepartment of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID 0009-0008-2053-4209
Ragavi LingamDepartment of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID 0009-0002-7237-8160
Tintu VargheseThe Wellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, India.ORCID 0000-0001-5246-5043

Funding

PATH Global Vaccine's Solution USA (RV5-IRIS-BRV Effectiveness & Intussusception) GAT.1822-01664506-CRT
6 · The paper itself

Abstract

objectivesOn April 7, 2018, the rotavirus (RV) vaccine was introduced into the Universal Immunization Program of Jharkhand. This study was undertaken to describe the epidemiology, sociodemography, and clinical and genotypical distribution of children aged < 5 y with acute gastroenteritis (AGE) in Dhanbad, Jharkhand.

methodsThis hospital-based, prospective, observational study was performed across three hospitals in Dhanbad between December 2019 and December 2023. Admitted children with AGE aged < 5 y were included, and data for all enrolled children (as defined in the study protocol) were captured. The collected stool samples were tested for RV, and positive samples were genotyped.

resultsOf the 591 children enrolled, 510 stool samples were eligible for RV testing; 237 (46.5%) children were found to be RV-positive, of whom 103 (57.2%) were aged 12-23 mo. The odds of developing RV gastroenteritis were 1.26 times higher in females than males (95% CI: 0.86-1.85; p = 0.22). G2P[4] was the most prevalent strain in RV-positive children, followed by G3P[8].

conclusionsThe results of this study confirm that diarrhea remains an important cause of hospitalization in children aged < 5 y; additionally, the impact of untreated drinking water among hospitalized children with diarrhea is high. The changing genotypic distribution pattern of RV emphasizes the need for continued surveillance and the detection of new genotypes.

Indexed as

DiarrheaGastroenteritisRotavirusRotavirus InfectionsAcute DiseaseChild, PreschoolFecesFemaleGenotypeHospitalizationHumansIndiaInfantMaleProspective StudiesAcute gastroenteritisEpidemiologyGenotypeRotavirusSurveillance

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.