Evidence map›Paper›PMID 41273534›Full record

ArticleObesity surgery2026

Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Risk-Adjusted Safety Profiles after Previous Fundoplication: A 499-Patient MBSAQIP Analysis.

Pattharasai Kachornvitaya, Valentin Mocanu, Mélissa V Wills, Juan S Barajas-Gamboa, Salvador Navarrete, Ricard Corcelles, Andrew Strong, Suthep Udomsawaengsup, Matthew Kroh, Jerry Dang

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Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Pattharasai KachornvitayaDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Valentin MocanuDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Mélissa V WillsDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Juan S Barajas-GamboaDigestive Diseases Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Salvador NavarreteDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Ricard CorcellesDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Andrew StrongDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Suthep UdomsawaengsupDepartment of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Matthew KrohDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA.
Jerry DangDigestive Disease Institute, Cleveland Clinic, Ohio, Cleveland, USA. dangj3@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity and gastroesophageal reflux disease (GERD) frequently coexist and may necessitate surgical intervention when conservative management fails. While fundoplication is effective for GERD, many patients ultimately require metabolic and bariatric surgery (MBS) for obesity. The safety and prevalence of sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) after prior fundoplication remains poorly characterized.

objectivesTo assess the prevalence and 30-day serious complication rates of SG and RYGB following fundoplication, and to identify independent predictors of adverse outcomes.

methodsA retrospective analysis of the 2022–2023 MBSAQIP database identified 499 patients undergoing primary SG or RYGB after fundoplication. Outcomes assessed included leak, bleeding, reoperation, reintervention, cardiac events, pneumonia, kidney injury, thromboembolism, infection, or sepsis. Multivariable logistic regression was used to adjust for baseline differences.

resultsOf 499 patients, 126 (25.3%) underwent SG (F-SG) and 373 (74.7%) underwent RYGB (F-RYGB). Concomitant paraesophageal hernia repair was more common in the F-RYGB group (54.2% vs. 26.2%, p < 0.001). Mean BMI was higher in F-SG (42.4 vs. 40.1 kg/m², p < 0.001). Weight gain and GERD were the leading indications for revisional bariatric surgery. F-RYGB was associated with longer operative times, hospital stay, and higher rates of reoperation, readmission, bowel obstruction, and serious complications (9.6% vs. 4.0%, p = 0.045). Rates of anastomotic leak, postoperative bleeding, and composite wound complications were low but numerically higher in F-RYGB, without statistical significance. In multivariate analysis, procedure type was not significantly associated with serious complications (OR 2.03, 95% CI 0.68–6.09, p = 0.207).

conclusionsBoth SG and RYGB appear to be safe and effective revisional options, and a history of fundoplication should not be considered a contraindication. Although RYGB was associated with longer operative times and higher early complication rates, multivariable analysis showed no significant difference in serious complications between the two procedures.

Indexed as

FundoplicationGastrectomyGastric BypassGastroesophageal RefluxObesity, MorbidPostoperative ComplicationsAdultFemaleHumansMaleMiddle AgedReoperationRetrospective StudiesFundoplicationGastroesophageal reflux diseaseRevisional bariatric surgeryRoux-en-Y gastric bypassSleeve gastrectomy

Identifiers

PMID41273534
PMCPMC12852177

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.