Evidence map›Paper›PMID 41273520›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Fundamental Kinetic Studies for Understanding Chiral Separations in High-Performance Liquid Chromatography.

Simona Felletti, Chiara De Luca, Martina Catani, Alberto Cavazzini

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simona FellettiDepartment of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy.
Chiara De LucaDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy.
Martina CataniDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy.
Alberto CavazziniDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy. cvz@unife.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiral recognition is a very complex phenomenon which depends on the nature of analytes and chiral selectors. Indeed, only enantiomers with proper and specific spatial orientation are able to interact with chiral adsorption sites on the selector. As a consequence, under defined conditions, it could happen that enantiorecognition mechanism takes a long time, leading to a worsening of the chromatographic efficiency. To shed light on the specific phenomena at the basis of this strange behavior, and hence to increase our knowledge of chiral separations, kinetic investigations can be applied.

Indexed as

Chromatography, High Pressure LiquidAdsorptionKineticsStereoisomerismChiral liquid chromatographyEnantiomers separationvan Deemter curve

Identifiers

PMID41273520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.