ReviewMethods in molecular biology (Clifton, N.J.)2026
Cinchona Alkaloid-Based Zwitterionic Chiral Stationary Phases Applied for Liquid Chromatographic Enantiomer Separations: An Overview.
Review in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By the early 2000s, chromatographic methods applying chiral stationary phases (CSPs) became the most effective techniques for the resolution of chiral compounds on both analytical and preparative scales. Nowadays, high-performance liquid chromatography (HPLC) employing various types of chiral selectors covalently bonded to silica-based supports, leading to the respective CSPs and the packed chromatographic columns thereof, offers a state-of-the-art methodology for enantioselective "chiral analysis." Although a large number of CSPs are commercially available, the design and development of new "chiral columns" are still mandatory since it is obvious that in practice one needs an even more well-balanced portfolio of different "chiral columns" to face the challenging tasks of enantiomeric resolutions. The development of the unique chiral anion, cation, and zwitterion exchangers achieved by Lindner and his partners serves as an expansion of the range of efficiently applicable CSPs.In this chapter, we present an updated and, in parts, text-wise renewed overview of our earlier chapter of this book series (Ilisz et al. (2019) Cinchona alkaloid-based zwitterionic chiral stationary phases applied for liquid chromatographic enantiomer separations: an overview. In: Scriba GKE (ed) Chiral seperations. Methods and protocols. Humana Press, pp 251-277. https://doi.org/10.1007/978-1-4939-9438-0 ) in discussing and summarizing direct enantiomer separations achieved by zwitterionic ion exchangers derived from Cinchona alkaloids, focusing on the literature published between 2018 and 2023. This article aims to provide comprehensive information on practical solutions for challenging enantiomer separations while discussing more generally the molecular recognition and methodological variables of these particular types of CSPs.
Indexed as
Identifiers
41273519What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.