Evidence map›Paper›PMID 41273483›Full record

ArticleGeroScience2026

Effects of aging on transmission from Ia afferents to α-motoneurons and presynaptic mechanisms across muscle lengths and contraction types.

Yohan Betus, Julian Colard, Marc Jubeau, Anne-Sophie Boureau, Guillaume Chapelet, Christophe Cornu, Thomas Cattagni

Abstract read
In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yohan BetusMovement - Interactions - Performance, MIP, UR 4334, Nantes Université, F-44000, Nantes, France.
Julian ColardMovement - Interactions - Performance, MIP, UR 4334, Nantes Université, F-44000, Nantes, France.
Marc JubeauMovement - Interactions - Performance, MIP, UR 4334, Nantes Université, F-44000, Nantes, France.
Anne-Sophie BoureauPôle de Gérontologie Clinique, Nantes Université, CHU Nantes, Nantes, France.
Guillaume ChapeletPôle de Gérontologie Clinique, Nantes Université, CHU Nantes, Nantes, France.
Christophe CornuMovement - Interactions - Performance, MIP, UR 4334, Nantes Université, F-44000, Nantes, France.
Thomas CattagniMovement - Interactions - Performance, MIP, UR 4334, Nantes Université, F-44000, Nantes, France. thomas.cattagni@univ-nantes.fr.ORCID http://orcid.org/0000-0002-6650-8339

Funding

Agence Nationale de la Recherche ANR-22-CE17-0002
6 · The paper itself

Abstract

Presynaptic inhibition of Ia afferents, particularly via primary afferent depolarization (PAD), plays a crucial role in modulating transmission from Ia afferents to α-motoneurons according to task demands. In young adults, PAD is enhanced during eccentric contractions and at longer muscle lengths, supporting adaptable motor control. However, aging is associated with reduced muscle spindle sensitivity, which may impair the regulation of presynaptic inhibition via PAD. This study investigated whether aging alters the modulation of PAD according to contraction type and muscle length. Nineteen older adults (69 ± 4 years) and 16 young adults (23 ± 2 years) participated in three experimental sessions. The maximal H-reflex (H

Indexed as

AgingMotor NeuronsMuscle ContractionMuscle, SkeletalSynaptic TransmissionAdultAgedElectromyographyFemaleH-ReflexHumansMalePresynaptic TerminalsYoung AdultEccentricH-reflexIa afferentLong muscle lengthPresynaptic inhibition

Identifiers

PMID41273483
PMCPMC13601482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.