ReviewResults and problems in cell differentiation2026
Evolution and Development of Insect Metamorphosis: A Case of Genetic Accommodation?
Review in Results and problems in cell differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- 20-Hydroxyecdysone-ResponsiveInsects · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For centuries, the evolution of complete metamorphosis in insects (holometaboly) has captured the imagination of philosophers and scientists. Recent discoveries using model organisms and experimental organisms have greatly advanced our understanding of the molecular regulators of metamorphosis. Drawing on these discoveries and insights gained from the evolution of direct development and metamorphosis in other taxa, we propose that the larval stage found in holometabolous insects may have evolved from a developmentally plastic embryo through the process of genetic accommodation. We highlight the need to study additional species that are phylogenetically closer to the hypothetical common ancestor of holometabolous insects and can serve as a surrogate for this hypothetical insect.
Indexed as
Identifiers
41273391What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.