ArticleEnvironmental science & technology2025
Effects of Exposure to Ambient Air Pollution on Human Metabolome in Patients with Coronary Artery Disease.
Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Urinary Metabolomic Alterations Associated with Contrasting Ambient Air Pollution Exposure in Thai Adults: An UntargetedInternational journal of molecular sciences · 2026Article
- Blood metabolomic signatures linking air pollution to lung cancer in the Cancer Prevention Studies.Nature communications · 2026Article
- High-resolution metabolomics of maternal polybrominated diphenyl ethers (PBDE) exposure and preterm birth in the Atlanta African American Maternal-Child Cohort.Communications medicine · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Despite the established associations between air pollution and cardiovascular diseases (CVD), the biological mechanisms underlying its toxic effects remain largely unknown. We investigated whether exposure to both short- and long-term ambient air pollutants is associated with systemic perturbations in the human metabolome. Using a metabolome-wide association (MWAS) study framework with pathway enrichment and chemical annotation, we analyzed plasma samples from 244 patients with coronary artery disease (CAD) in the Emory Cardiovascular Biobank cohort. Individual residential exposures to air pollutants carbon monoxide (CO), nitrogen oxides (NO
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Registered trials
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