Evidence map›Paper›PMID 41272917›Full record

ArticleBMC psychology2025

The association between caregiving for disabled spouses and depressive symptoms among middle-aged and older adults in China.

Tingyu Mu, Guiyue Ma, Rixiang Xu

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Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Tingyu Mu *School of Nursing, Anhui Medical University, Hefei, 230032, China.
Guiyue Ma *School of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, China.
Rixiang XuSchool of Medical Humanities, Anhui Medical University, Hefei, 230032, China. ahmusop@126.com.

Funding

Anhui Province Social Science Innovation and Development Research Project 2024CXQ028
6 · The paper itself

Abstract

backgroundIt is widely recognized that individuals with disabilities are at a significantly higher risk of mental health issues. However, the mental health status of their spousal caregivers often tends to be overlooked.

objectiveTo investigate the association between caring for a disabled spouse and depressive symptoms among middle-aged and older adults, and to assess whether this association differs by caregiver gender.

methodsCross-sectional data were drawn from the 2020 China Health and Retirement Longitudinal Study (CHARLS). Depressive symptoms in respondents were measured by the CESD-10. Associations were estimated using generalized estimating equations (GEE) with a logit link to account for intra-household correlation. Models adjusted for sociodemographic and health-related confounders. We conducted gender-stratified analyses, tested the interaction between gender and caregiving, performed an analysis restricted to caregivers (n = 1,357), and examined the relation between the number/types of recipient disabilities and caregiver depressive symptoms.

resultsIn multivariable GEE models, spousal caregiving was associated with higher odds of depressive symptoms (OR = 1.278, 95% CI 1.127 to 1.449, P < 0.001). Stratified analyses indicated a stronger association among female caregivers (OR = 1.459, 95% CI 1.204 to 1.768, P < 0.001) than male caregivers (OR = 1.207, 95% CI 1.013 to 1.438, P = 0.036); however, the gender × caregiving interaction was not statistically significant (P = 0.271). Within the caregiver subsample, female caregivers had markedly higher odds of depressive symptoms compared with male caregivers (OR = 1.824, 95% CI 1.355 to 2.455). Moreover, a greater number or severity of recipient disabilities was associated with incrementally higher depressive risk among caregivers, suggesting a dose-response relationship.

conclusionsSpousal caregiving was associated with elevated odds of depressive symptoms, with larger effect estimates among women. Limitations include cross-sectional design, self-reported measures, and potential residual confounding. Prospective studies are needed to assess temporality and causal pathways; the results support enhanced monitoring and development of targeted supports for spousal caregivers, with consideration of sex differences and recipient disability burden.

Indexed as

CaregiversDepressionPersons with DisabilitiesSpousesAgedChinaCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedSex FactorsDepressive symptomsFamily caregiverFunctional disabilityGender

Identifiers

PMID41272917
PMCPMC12639645

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.