Evidence map›Paper›PMID 41272793›Full record

ArticleHarm reduction journal2025

Developing and testing a digital harm reduction app for GBMSM engaging in chemsex: a feasibility study grounded in users' lived experiences.

Carol Strong, Patricia Anne Joson, Poyao Huang, Chuan-Chih Chen, Chia-Wen Li, Yuan-Chi Tseng, Tsan-Tse Chuang, Huei-Jiuan Wu, Stephane Wen-Wei Ku

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carol StrongDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan. carol.chiajung@gmail.com.
Patricia Anne JosonDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Poyao HuangInstitute of Health Behavior and Community Sciences, National Taiwan University, Taipei, Taiwan.
Chuan-Chih ChenIn the Know Marketing Ltd., Kaohsiung, Taiwan.
Chia-Wen LiCenter for Infection Control and Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yuan-Chi TsengAIMS Fellows, National Tsing Hua University, Hsinchu, Taiwan.
Tsan-Tse ChuangDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Huei-Jiuan WuThe Kirby Institute, University of New South Wales, Sydney, Australia.
Stephane Wen-Wei KuDivision of Infectious Diseases, Department of Medicine, Taipei City Hospital Renai Branch, Taipei, Taiwan.

Funding

National Science and Technology Council NSTC 112-2314-B-006-081-MY3
6 · The paper itself

Abstract

backgroundChemsex, involving substances like methamphetamine, GHB/GBL, and mephedrone among gay, bisexual, and other men who have sex with men (GBMSM), poses HIV and health concerns. Despite existing integrated care programs, uptake remains low, highlighting a missed opportunity for self-help harm-reduction digital strategies. This study employs a collaborative design approach, integrating insights from the community on the app prototype and assessed usability to guide future interventions.

methodsThe app prototype was built on two design principles: recovery as a continuum with evolving goals like harm reduction and temporarily not using, and harm reduction dimensions on drug-, sex-, and HIV-related harms. Features were integrated into UPrEPU, a user-centered app supporting HIV PrEP adherence through flexible dosing and personalized reminders. Users could set goals, such as reducing chemsex frequency, supported by tailored feedback. The app includes an emergency alert system, local resources for clean needles and HIV testing, and myth-busting for the chemsex community. GBMSM with recent chemsex experience tested the app between January-December 2024. A one-month evaluation followed using the mHealth App Usability Questionnaire (1-7 scale, lower score indicates higher usability) and an interview to assess usability and impact. Interview transcripts were analyzed based on design themes to gather users' reflections and suggestions for enhancing harm reduction features.

resultsTwenty GBMSM aged 23-46 in Taiwan reported a positive perception of usability (mean = 2.14, SD = 1.15). However, users indicated that HIV PrEP functions were utilized more frequently than drug-related functions. Dynamic goal setting should be more intuitive and tied to lived experiences, reflecting one's physical and mental state. Inadequate social support led individuals to adopt self-reliance strategies, such as tracking HIV PrEP uptake, setting hydration reminders, and prioritizing self-care. This extended to managing cravings, adhering to dosage limits, and achieving control over their health. Users emphasized the need for tools to go beyond drug-related features, focusing instead on helping them plan their time and set broader life goals, supporting a more holistic approach to well-being.

conclusionsA collaborative, user-centered approach to app design shows promise for digital solutions addressing chemsex-related harms, including HIV prevention, with functions closely tied to lived experiences.

Indexed as

Harm ReductionHomosexuality, MaleMobile ApplicationsSexual and Gender MinoritiesAdultChemsexFeasibility StudiesHIV InfectionsHumansMaleMethamphetamineMiddle AgedPre-Exposure ProphylaxisYoung AdultMethamphetamine

Identifiers

PMID41272793
PMCPMC12639721

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.