Evidence map›Paper›PMID 41272774›Full record

ArticleTrials2025

Mental health first aid training to improve depression literacy among health ambassadors in Iran: study protocol for a cluster-randomized controlled trial.

Fatemeh Hallajian, Ensiyeh Jamshidi, Azadeh Sayarifard, Laleh Ghadirian, Ayat Ahmadi

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Fatemeh HallajianDepartment of Health Education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ensiyeh JamshidiDepartment of Health Education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. ensiyeh_jamshidi@yahoo.com.
Azadeh SayarifardCenter for Academic and Health Policy, Tehran University of Medical Sciences, Tehran, Iran.
Laleh GhadirianKnowledge Utilization Research Center, Center for Academic and Health Policy, Tehran University of Medical Sciences, Tehran, Iran.
Ayat AhmadiKnowledge Utilization Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Funding

Tehran University of Medical Sciences and Health Services 69583
6 · The paper itself

Abstract

BACKGROUND AND

objectiveOne of the strategies for enhancing the mental health literacy of the community could be capacity building in the field of mental health first aid (MHFA) training among health ambassadors, who serve as volunteers between health service providers and families. The present study aims to investigate the effectiveness of MHFA training packages for depression prevention using critical thinking methods on the depression literacy (as a key component of mental health literacy) of health ambassadors to assist in the early identification and timely referral of individuals with depressive disorders. Depressive disorders are among the most prevalent mental health conditions, yet many individuals delay or avoid seeking treatment due to stigma and limited awareness. Improving mental health literacy is therefore essential to promote early recognition and timely help-seeking. Health ambassadors, as community volunteers linking families to health services, are uniquely positioned to support this goal. This study applies a culturally adapted MHFA training package for depression, delivered through critical thinking and role playing, in improving the depression literacy (as a key component of mental health literacy) of health ambassadors. The trial seeks to determine whether this approach enhances their ability to recognize symptoms, provide initial support, and facilitate referral to professional care. METHODOLOGY: This is a study protocol for a cluster-randomized controlled trial conducted in 10 comprehensive health service centers (CHSCs) in Islamshahr, Iran. A computer-generated random sequence will assign five centers to the intervention group and five to the control group. The allocation sequence will be prepared and concealed by an independent epidemiologist not involved in recruitment or intervention delivery. From each center, 25 eligible health ambassadors (women aged 25-45 years with ≥ 2 years of experience) will be randomly selected, yielding a total sample of 250 participants. The intervention group will receive an eight-session, culturally adapted MHFA training package delivered using problem-based learning and role-playing methods. Depression literacy (as a key component of mental health literacy) will be assessed at baseline and 2 months post-intervention using the questionnaire developed by Reavley et al. (2014). For statistical inference, analysis of covariance (ANCOVA) will be employed to examine group differences, and multivariate linear regression will be applied to adjust for potential confounders, using SPSS software version 24. A p-value of < 0.05 will be considered statistically significant. DISCUSSION: This protocol describes a trial designed to evaluate whether mental health first aid (MHFA) training with a critical thinking approach can improve depression literacy (as a key component of mental health literacy) among health ambassadors. Findings from this study may provide evidence to guide future mental health promotion strategies, particularly for the early identification and referral of individuals with depression and the prevention of suicide.

trial registrationIran Randomized Clinical Trial Center IRCT20231225060521N1. Registered on 21 January 2024 (current status: ongoing).

Indexed as

Community Health WorkersDepressionFirst AidHealth Knowledge, Attitudes, PracticeHealth LiteracyMental HealthHumansIranMulticenter Studies as TopicRandomized Controlled Trials as TopicCritical thinkingDepressionDepression literacyExperiential learningHealth ambassadorMental health first aidMental health literacyProblem-based learningRole playing

Identifiers

PMID41272774
PMCPMC12639782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.