ArticleBMC nephrology2025
The association between computed tomography-based intrapancreatic fat deposition and renal function.
Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Fatty Pancreas and Risk of Type 2 Diabetes, Chronic Kidney Disease and Cardiovascular Events: Evidence From a Population-Based Cohort.United European gastroenterology journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundEctopic fat deposition in non-adipose organs is increasingly recognized as a driver of chronic metabolic disease, yet the relationship between intrapancreatic fat and impaired renal function remains poorly defined. We investigated whether pancreatic steatosis, quantified by computed-tomography (CT) attenuation, is independently associated with impaired renal function in a large Chinese health-screening cohort.
methodsThis cross-sectional study included adults (≥ 20 years) who underwent low-dose chest CT and same-day serum creatinine measurement at the Nanjing University of Chinese Medicine between 2018 and 2021. Pancreatic fat was assessed by mean CT attenuation (PanCT) and the pancreas-to-spleen attenuation ratio (P/S). Impaired renal function was defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m².
resultsAmong 9,432 participants (mean age 51.6 ± 15.4 years; 60.7% male), 232 (2.5%) had CKD. Both PanCT and P/S decreased monotonically with increasing impaired renal function prevalence across quartiles (p-trend < 0.001). The highest quartiles of PanCT (> 50.2 HU) and P/S (> 1.03) were associated with 48% (OR 0.52; 95% CI 0.27–0.99) and 54% (OR 0.46; 95% CI 0.23–0.90) lower odds of impaired renal function, respectively, compared with the lowest quartiles. Restricted cubic splines revealed a linear inverse relationship, and subgroup analyses confirmed consistency in non-diabetic, non-hypertensive, and high-liver-fat individuals.
conclusionsGreater intrapancreatic fat deposition is independently associated with increased risk of impaired renal function in Chinese adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.