ArticleBMC geriatrics2025
Assessing frailty to predict surgical risk: a comparative study of three tools in older non-cardiac surgery patients.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07522541 (Comparative Analysis of ASA Score and Clinical Frailty Scale in Predicting Postoperative Intensive Care Requirements in Geriatric Hip Fracture Surgery), which is not on this map. Cited by 3 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Analysis of ASA Score and Clinical Frailty Scale in Predicting Postoperative Intensive Care Requirements in Geriatric Hip Fracture Surgery
Who cites it
3 citing papers in PubMed.
- Comparative Analysis of the ASA-PS Score and Clinical Frailty Scale in Predicting Postoperative Intensive Care Unit Requirement in Geriatric Hip Fracture Surgery: A Retrospective Evaluation.Journal of clinical medicine · 2026Article
- Evaluating the Diagnostic Value of Clinical and Laboratory Parameters in Older Adults with Abdominal Pain: A Retrospective Analysis of CT Predictors.Medicina (Kaunas, Lithuania) · 2026Article
- Complex Oncologic Surgery in a Nonagenarian With Severe Aortic Stenosis: Integration of Enhanced Recovery After Surgery Protocol, Total Intravenous Anesthesia, and Advanced Hemodynamic Monitoring.Journal of medical cases · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is a significant predictor of adverse outcomes in older surgical patients. this study, we aimed to evaluate the feasibility and predictive ability of the Clinical Frailty Scale (CFS), Modified Frailty Index-11 (mFI-11), and FRAIL scale for postoperative complications in older Thai patients who underwent intermediate- to high-risk non-cardiac surgery.
methodsThis prospective cohort study included 637 older patients (aged ≥ 60 years) scheduled for intermediate- to high-risk elective non-cardiac surgery. Frailty was assessed preoperatively using the CFS, mFI-11, and FRAIL scale. Postoperative complications were defined as Clavien-Dindo classification ≥ 2. Predictive performance was analyzed using logistic regression and the area under the receiver operating characteristic curve (AUC).
resultsThe mean age of participants was 70.5 years (standard deviation 7.68), and 48% were male. Frailty was significantly associated with higher rates of postoperative complications across all tools: CFS (44.9% vs. 22.2%), mFI-11 (57.8% vs. 26.9%), and FRAIL scale (56.3% vs. 26.0%) (all p < 0.001). In multivariable logistic regression, the CFS was the only independent predictor (odds ratio 2.39, 95% confidence interval [CI]: 1.42-4.00, p < 0.001). Area under the curve (AUC) values were 0.635 (95% CI: 0.5902-0.6794) (mFI-11), 0.632 (95% CI: 0.5881-0.6756) (FRAIL scale), and 0.619 (95% CI: 0.5742-0.6637) (CFS), compared with 0.657 (95% CI: 0.6152-0.6988) of the American Society of Anesthesiologists (ASA) classification. Combining frailty tools with ASA improved predictive accuracy, with CFS + ASA exhibiting the highest AUC (0.704, 95% CI: 0.660-0.748).
conclusionFrailty assessed with the CFS, mFI-11, and FRAIL scale was associated with postoperative complications, with the CFS demonstrating the strongest independent predictive value. Incorporating frailty screening into preoperative evaluation, especially combined with ASA classification, can improve risk stratification and perioperative care.
trial registrationTCTR20210706002.
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