Evidence map›Paper›PMID 41272509›Full record

SynthesisBMC infectious diseases2025

Microalbuminuria among HIV/AIDS patients in Africa: a systematic review and meta-analysis.

Ousman Mohammed, Habtu Debash, Melaku Ashagrie Belete, Alemu Gedefie, Mihret Tilahun, Zewudu Mulatie, Bruktawit Eshetu, Saba Gebremichael Tekele, Hussen Ebrahim, Daniel Gebretsadik Weldehanna and 2 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Ousman MohammedDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. ousmanabum@gmail.com.
Habtu DebashDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Melaku Ashagrie BeleteDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Alemu GedefieDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Mihret TilahunDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Zewudu MulatieDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Bruktawit EshetuDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Saba Gebremichael TekeleDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Hussen EbrahimDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Daniel Gebretsadik WeldehannaDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Agumas ShibabawDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.
Ermiyas AlemayehuDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOver the past decade, the incidence of chronic kidney disease among HIV-seropositive people has increased at an alarming rate. Microalbuminuria is believed to be a precursor of HIV-related renal disease; early detection with intervention may prevent end-stage renal disease. Therefore, the current study was aimed at determining the pooled prevalence of microalbuminuria among HIV patients in Africa.

methodsWe accessed Google Scholar, PubMed, the Cochrane Library, EMBASE, the Web of Science, ScienceDirect, and ResearchGate to get the original research articles. We employed the I² and Cochran's Q test to assess the presence of heterogeneity between studies. Publication bias was checked by using a funnel plot and Egger's regression test. The pooled prevalence was estimated using the random-effects model. We ran the sensitivity analysis to see if there were outlier results in the included studies. Moreover, subgroup analysis was also done.

resultsThe current meta-analysis includes 16 studies with 3588 individuals. In Africa, the overall pooled prevalence of microalbuminuria in both adults and children was 22.25% (95% CI 17.38-27.13; I

conclusionThe present review study found that over one-fourth of HIV-infected patients had microalbuminuria, indicating a considerable burden of subclinical kidney disease. Therefore, HIV patients need to be screened early for microalbuminuria to prevent further renal complications. PROTOCOL REGISTRATION: It has been registered in the PROSPERO database with a registration number of CRD42023446664. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

AlbuminuriaHIV InfectionsAdultAfricaFemaleHumansMalePrevalenceAcquired immunodeficiency syndromeHuman immunodeficiency virusMeta-analysisMicroalbuminuria

Identifiers

PMID41272509
PMCPMC12751774

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.