Evidence map›Paper›PMID 41272410›Full record

ArticleJournal of applied clinical medical physics2025

Enhancement of dose distribution using tissue compensators in boron neutron capture therapy.

Akinori Sasaki, Naonori Hu, Mai Nojiri, Kazuhiko Akita, Syuushi Yoshikawa, Yasushi Kohigashi, Keiji Nihei, Teruhito Aihara, Satoshi Takeno, Yuki Yoshino and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Akinori SasakiKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.ORCID https://orcid.org/0000-0002-8236-2405
Naonori HuKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.ORCID https://orcid.org/0000-0003-2702-3344
Mai NojiriKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Kazuhiko AkitaKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Syuushi YoshikawaBNCT Joint Clinical Institute, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Yasushi KohigashiKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Keiji NiheiKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Teruhito AiharaKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Satoshi TakenoKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Yuki YoshinoKansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Hiroki TanakaInstitute for Integrated Radiation and Nuclear Science, Kyoto University, Kyoto, Japan.
Koji OnoBNCT Joint Clinical Institute, Osaka Medical and Pharmaceutical University, Osaka, Japan.

Funding

JSPS KAKENHI JP24K18810
6 · The paper itself

Abstract

In BNCT for head and neck tumors delivered with a horizontal beam, the presence of missing tissue near the beam path can cause reduction in neutron fluence rate in adjacent tissue regions due to the loss of scattered neutrons. These regions are referred to as neutron depleted areas. By placing a tissue equivalent compensator in these missing tissue regions, the lateral scatter equilibrium is partially restored, increasing the local neutron fluence rate and, consequently, the dose to the target volume while maintaining normal tissue exposure within tolerance limits.

Indexed as

Boron Neutron Capture TherapyHead and Neck NeoplasmsHumansNeutronsOrgans at RiskRadiotherapy DosageRadiotherapy Planning, Computer-AssistedScattering, RadiationBNCTmonte carlo simulationneutron scattertissue compensator

Identifiers

PMID41272410
PMCPMC12638218

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.