Evidence map›Paper›PMID 41272091›Full record

ArticleScientific reports2025

Chemical finger-printing, antioxidant activity and in silico validation of phytometabolites of Octhochloa compressa.

Jawaria Aslam, Tariq Hussain, Mirza Imran Shahzad, Hafiz Muhammad Ali, Maria Aslam, Muhammad Shahid, Athar Jamal, Umer Farooq, Saima Asif, Kasim Sakran Abass and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jawaria AslamDepartment of Physiology & Biochemistry, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, 63100, Pakistan.
Tariq HussainDepartment of Basic Sciences, College of Veterinary and Animal Science, Jhang, Pakistan.
Mirza Imran ShahzadInstitute of Biochemistry, Biotechnology & Bioinformatics, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan. mirza.imran@iub.edu.pk.
Hafiz Muhammad AliFaculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan. hmali_uaf@hotmail.com.
Maria AslamDepartment of Computing, Tahseen Ahmad Cheema Institute, Bahawalpur, 63100, Pakistan.
Muhammad ShahidDepartment of Biochemistry, University of Agriculture, Faisalabad, 38000, Pakistan.
Athar JamalDepartment of Chemistry, The University of Lahore, Lahore, 54590, Pakistan.
Umer Farooq8Department of Computer Science, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, 63100, Pakistan.
Saima AsifInstitute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Kasim Sakran AbassDepartment of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Kirkuk, Kirkuk, 36013, Iraq.
Dalia FouadDepartment of Zoology, College of Science, King Saud University, Riyadh, 11495 , PO Box 22452, Saudi Arabia. dibrahim@ksu.edu.sa.
Farid Shokry AtayaDepartment of Biochemistry, College of Science, King Saud University, Riyadh, 11451 , PO Box 2455, Saudi Arabia.
Konul AhmadovaDepartment of Life Sciences, Western Caspian University, Baku, AZ1001, Azerbaijan.
Zaid ChacharSchool of Data Science, The Chinese University of Hong Kong, Shenzhen, 518172, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study focused on evaluating the antioxidant properties of Octhochloa compressa, a Cholistani medicinal plant and to explore the interaction of its active phytochemical constituents with the biological macromolecule NADPH oxidase (PDB ID: 2CDU). Six different non-polar to polar solvent extracts were evaluated for their antioxidant activity using DPPH and FRAP assays. The key metabolites were then subjected to molecular docking against NADPH oxidase, density functional theory (DFT) and molecular dynamics (MD) simulations to validate the ligand-protein stability and conformational dynamics. The methanol extract revealed significantly highest scavenging potential (IC

Indexed as

AntioxidantsPhytochemicalsPlant ExtractsFlavonoidsMolecular Docking SimulationMolecular Dynamics SimulationNADPH OxidasesAntioxidantsFlavonoidsNADPH OxidasesPhytochemicalsPlant ExtractsDFTGC-MSHPLCMD simulationsMolecular dockingNADPH oxidaseOcthochloa compressa

Identifiers

PMID41272091
PMCPMC12639017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.