Evidence map›Paper›PMID 41271765›Full record

ArticleNature communications2025

ARMH2 is a cytosolic component of CatSper crucial for sperm function.

Qingqing Zhao, Shiyi Lin, Hang Kang, Yanfei Ru, Qikui Xu, Zijing Yu, Xiaofang Huang, Carlo De Rito, Giulia Sassi, Shaojie Wang and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Molecular basis of the higher-order assembly of CatSper.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Qingqing Zhao *Fudan University, Shanghai, China.
Shiyi Lin *Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-9026-8275
Hang Kang *Institute of Reproductive Medicine, Medical school, Nantong University, Nantong, Jiangsu, China.
Yanfei RuWestlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
Qikui XuKey Laboratory of Structural Biology of Zhejiang Province, State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
Zijing YuWestlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0009-0005-1697-3872
Xiaofang HuangDepartment of Cellular and Molecular Physiology, Yale School of Medicine, Yale University, New Haven, CT, USA.
Carlo De RitoDepartment of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.
Giulia SassiDepartment of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.ORCID http://orcid.org/0000-0002-2600-9092
Shaojie WangKey Laboratory of Structural Biology of Zhejiang Province, State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
Shuya SunState Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.
Rui SunSchool of Medicine, Westlake University, Hangzhou, Zhejiang, China.
Honghan ChengSchool of Medicine, Westlake University, Hangzhou, Zhejiang, China.
Yi ZhuSchool of Medicine, Westlake University, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0003-0429-0802
Mingxi LiuState Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, China.ORCID http://orcid.org/0000-0001-6499-7899
Yongdeng ZhangWestlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-4569-8137
Min JiangWestlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.ORCID http://orcid.org/0000-0002-7005-937X
Riccardo PercudaniDepartment of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.ORCID http://orcid.org/0000-0001-8452-1062
Jean-Ju ChungDepartment of Cellular and Molecular Physiology, Yale School of Medicine, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-8018-1355
Xuhui ZengInstitute of Reproductive Medicine, Medical school, Nantong University, Nantong, Jiangsu, China. zengxuhui@ntu.edu.cn.ORCID http://orcid.org/0000-0002-5936-4699
Zhen YanKey Laboratory of Structural Biology of Zhejiang Province, State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China. yanzhen@westlake.edu.cn.ORCID http://orcid.org/0000-0002-1999-8451
Jianping WuKey Laboratory of Structural Biology of Zhejiang Province, State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China. wujianping@westlake.edu.cn.ORCID http://orcid.org/0000-0001-9869-7691

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32271261Natural Science Foundation of Zhejiang Province (Zhejiang Provincial Natural Science Foundation) LDG25C050002Natural Science Foundation of Zhejiang Province (Zhejiang Provincial Natural Science Foundation) LR22C050003
6 · The paper itself

Abstract

Sperm capacitation and fertilization are highly regulated by Ca

Indexed as

Armadillo Domain ProteinsCalcium ChannelsFertilitySpermatozoaSperm CapacitationAnimalsCryoelectron MicroscopyCytosolFemaleMaleMiceMice, Inbred C57BLMice, KnockoutSperm MotilitySperm TailTestisArmadillo Domain ProteinsCalcium Channels

Identifiers

PMID41271765
PMCPMC12638846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.