Evidence map›Paper›PMID 41271758›Full record

ArticleNature communications2025

An integrated platform for liquid handling and cell imaging in life science applications.

Meryem Beyza Avci, Furkan Kocer, Fatma Kurul, Arif E Cetin

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Semiautomated Synthesis and Interactive Visualization of Zeolitic Imidazolate Framework-Based Biocomposites.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meryem Beyza AvciIzmir Biomedicine and Genome Center, Balcova, Izmir, Turkey.ORCID http://orcid.org/0000-0001-8701-2239
Furkan KocerIzmir Biomedicine and Genome Center, Balcova, Izmir, Turkey.ORCID http://orcid.org/0009-0003-5891-7436
Fatma KurulIzmir Biomedicine and Genome Center, Balcova, Izmir, Turkey.ORCID http://orcid.org/0000-0002-6394-3079
Arif E CetinIzmir Biomedicine and Genome Center, Balcova, Izmir, Turkey. arifengin.cetin@ibg.edu.tr.ORCID http://orcid.org/0000-0002-0788-8108

Funding

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu (Scientific and Technological Research Council of Turkey) 122E385
6 · The paper itself

Abstract

The increasing complexity of life science research requires laboratory tools that combine precision, automation, and accessibility. Conventional liquid handling and imaging systems are either separated or integrated at high cost, limiting their adoption in small-scale laboratories. Here we show that G-Bot, a compact five-axis platform, integrates automated liquid handling, live-cell imaging, and real-time data processing into a single system. G-Bot performs complex workflows, e.g., including cell seeding, drug dosing, media exchange, and long-term live-cell imaging, while maintaining stable culture conditions through integrated incubator and stage-top regulation modules. Its imaging capabilities span cells, organoids, and small organisms such as zebrafish larvae, providing high-content, physiologically relevant data. Unlike pipette-based systems, G-Bot employs a tubing-based dispensing mechanism for precise reagent delivery with minimal waste. By unifying liquid handling, imaging, and analysis, G-Bot streamlines laboratory-scale workflows, improves reproducibility, and bridges the gap between manual methods and costly industrial automation, offering broad utility in research and drug discovery.

Indexed as

Biological Science DisciplinesAnimalsAutomation, LaboratoryCell Culture TechniquesHumansLarvaOrganoidsReproducibility of ResultsWorkflowZebrafish

Identifiers

PMID41271758
PMCPMC12748592

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.