Evidence map›Paper›PMID 41271717›Full record

ArticleNature communications2025

Reconciling time and prediction error theories of associative learning.

Noé Hamou, Samuel J Gershman, Gautam Reddy

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. All cells have the capacity to time.Journal of experimental psychology. Animal learning and cognition · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noé HamouSainsbury Wellcome Centre for Neural Circuits and Behaviour and Gatsby Computational Neuroscience Unit, University College London, London, UK.ORCID http://orcid.org/0009-0006-1265-6770
Samuel J GershmanDepartment of Psychology, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-6546-3298
Gautam ReddyCenter for Brain Science, Harvard University, Cambridge, MA, USA. greddy@princeton.edu.ORCID http://orcid.org/0000-0002-1276-9613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Learning involves forming associations between sensory events that have a consistent temporal relationship. Influential theories based on prediction errors explain numerous behavioral and neurobiological observations but do not account for how animals measure the passage of time. Here, we propose a theory for temporal causal learning, where the structure of inter-stimulus intervals is used to infer the singular cause of a rewarding stimulus. We show that a single assumption of timescale invariance, formulated as an hierarchical generative model, is sufficient to explain a puzzling set of learning phenomena, including the power-law dependence of acquisition on inter-trial intervals and timescale invariance in response profiles. A biologically plausible algorithm for inference recapitulates salient aspects of both timing and prediction error theories. The theory predicts neural signals with distinct dynamics that encode causal associations and temporal structure.

Indexed as

Association LearningAlgorithmsAnimalsHumansModels, NeurologicalRewardTime Factors

Identifiers

PMID41271717
PMCPMC12638834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.