Evidence map›Paper›PMID 41271617›Full record

ArticleBlood cancer journal2025

Defining the proteome of bone marrow plasma in multiple myeloma and monoclonal gammopathy of undetermined significance.

Joel-Sean Hsu, Udit Yadav, Kishore Garapati, Kiran K Mangalaparthi, Yogesh Chawla, J Erin Wiedmeier-Nutor, Rafael Fonseca, P Leif Bergsagel, S Vincent Rajkumar, Shaji Kumar and 3 more

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Joel-Sean HsuDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.
Udit YadavDivision of Hematology and Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
Kishore GarapatiDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Kiran K MangalaparthiDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-5791-727X
Yogesh ChawlaDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-6679-518X
J Erin Wiedmeier-NutorDivision of Hematology and Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
Rafael FonsecaDivision of Hematology and Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.ORCID http://orcid.org/0000-0002-5938-3769
P Leif BergsagelDivision of Hematology and Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA.
S Vincent RajkumarDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-5862-1833
Shaji KumarDivision of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-5392-9284
Wilson I GonsalvesDivision of Hematology, Mayo Clinic, Rochester, MN, USA. Gonsalves.Wilson@mayo.edu.
Akhilesh PandeyDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Pandey.Akhilesh@mayo.edu.ORCID http://orcid.org/0000-0001-9943-6127
Richard K KandasamyDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Kandasamy.RichardKumaran@mayo.edu.ORCID http://orcid.org/0000-0002-0894-1222

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Keith L. Knutson · 1985 to 2026
$151.3M
Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Amylou Constance Dueck · 2015 to 2026
$25.5M
Mayo Clinic Center for Clinical ProteomicsU01CA271410 · NCI · MAYO CLINIC ROCHESTER · PI Rafael Fonseca, AKHILESH PANDEY · 2022 to 2026
$5.3M
Assessment of Metabolites Among Asymptomatic Precursor and Malignant Monoclonal GammopathiesR01CA254961 · NCI · MAYO CLINIC ROCHESTER · PI GONSALVES, WILSON · 2021 to 2024
$1.5M
Preclinical studies for the immunoprevention of multiple myelomaUG3CA290468 · NCI · MAYO CLINIC ARIZONA · PI Peter Leif Bergsagel, Marta Chesi · 2025 to 2026
$1.4M
NCI NIH HHS P30 CA015083NCI NIH HHS P50 CA186781NCI NIH HHS R01 CA254961NCI NIH HHS U01 CA271410NCI NIH HHS UG3 CA290468U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01CA254961U.S. Department of Health & Human Services | National Institutes of Health (NIH) U01CA271410U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) CA186781U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) CA254961U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) U01CA271410
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41271617
PMCPMC12639027

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.