Evidence map›Paper›PMID 41271599›Full record

ArticleJournal of feline medicine and surgery2026

Clinical trial of molnupiravir with or without an oral immune stimulant as a first-line treatment of feline infectious peritonitis.

Petra Černá, Steven Dow, Jennifer Hawley, McKenna Willis, Michael R Lappin

Abstract readClinical Trial, VeterinaryRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of feline medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Petra ČernáDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0002-4300-8534
Steven DowDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
Jennifer HawleyDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
McKenna WillisDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
Michael R LappinDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesThe aim of the present study was to evaluate the efficacy of oral molnupiravir (MPV; EIDD-2801) in cats with naturally occurring feline infectious peritonitis (FIP), with a subset of cats being administered a known immune stimulant (liposome-toll-like receptor agonist complex [LTC] orally.MethodsA prospective, open-label longitudinal single-center clinical trial was conducted. Cats with FIP were enrolled and treated with oral MPV (10-21 mg/kg PO q12h) for 84 days. A subset of cats (41 cats with effusive FIP) was randomized to concurrently be administered the oral immune stimulant. Cats were evaluated at 0, 4, 8 and 12 weeks followed by a 12-week observation period.ResultsA total of 73 cats were included in the study and 77% of the cats survived to 6 months. The median total bilirubin concentrations were significantly different (

Indexed as

Adjuvants, ImmunologicAntiviral AgentsCytidineFeline Infectious PeritonitisHydroxylaminesAdministration, OralAnimalsCatsDrug Therapy, CombinationFemaleMaleProspective StudiesTreatment OutcomeAdjuvants, ImmunologicAntiviral AgentsCytidineHydroxylaminesmolnupiravirAntiviralcoronavirushyperglobulinemiahypoalbuminemia

Identifiers

PMID41271599
PMCPMC12858776

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.