ReviewEnvironmental microbiology2025
Antibiotic Persister Cells in Acinetobacter baumannii: Overview of Molecular Mechanisms and Removal Strategies.
Review in Environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Time-resolved proteomic adaptation of multidrug-resistantMicrobiology spectrum · 2026Article
- Virulence and Resistance Mechanisms in Multidrug-ResistantPathogens (Basel, Switzerland) · 2026Review
- Repeated sub-MIC exposure and biofilm derivation are associated with resistance development and reduced bactericidal susceptibility in Aeromonas hydrophila KCTC 2358.Molecular biology reports · 2026Article
- Phenotype-Guided Nanotherapeutic Strategies for Carbapenem-ResistantPharmaceutics · 2026Review
- New Insights intoPathogens (Basel, Switzerland) · 2026Review
- Impact of an Antimicrobial Stewardship Program on Antibiotic Consumption, Bacterial Susceptibility, and Costs in a High-Complexity Public Hospital.Antibiotics (Basel, Switzerland) · 2026Article
- Salmonella enterica persister cells exhibit distinct susceptibility profiles following exposure to human serum and macrophages.PloS one · 2026Article
- Antibiotic Persister Cells in Acinetobacter baumannii: Overview of Molecular Mechanisms and Removal Strategies.Environmental microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Acinetobacter baumannii is a bacterium classified as 'Critical' by the World Health Organization due to the rapid development of antibiotic resistance leading to many therapeutic failures. However, the existence of persister bacterial subpopulations may also partly explain these therapeutic failures. Persister cells are a bacterial subpopulation that may survive to higher concentrations of antibiotics compared to isogenic individuals. This temporary and reversible phenotype may eventually lead to the development of new antibiotic resistance or to the recurrence of infection making it important to study. The mechanisms involved in the selection of persister cells are multiple and complex involving toxin/antitoxin systems, second messengers, the SOS response, the phenyl acetic catabolic pathway or membranes modifications. Some of these mechanisms, like toxin/antitoxin systems presenting a great diversity, appear to be species- or strain-specific. This review focuses on current advances in knowledge concerning the molecular mechanisms involved in the physiology of persister cells in A. baumannii, and the eradication strategies developed to combat this dormant subpopulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.