Evidence map›Paper›PMID 41271444›Full record

ArticleChemical biology & drug design2025

Identification of New CD36 Antagonists by Structure-Based Virtual Screening.

Sandra L Guerrero-Rodríguez, Luis Córdova-Bahena, Fabiola Cortés-Mendoza, Angel J Ruiz-Moreno, Cecilia Mata-Cruz, Mireya Velázquez-Paniagua, Nohemí Salinas-Jazmín, Martín González-Andrade, Marco A Velasco-Velázquez

Abstract read
In one paragraph

Article in Chemical biology & drug design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sandra L Guerrero-RodríguezDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Luis Córdova-BahenaDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID https://orcid.org/0000-0003-2666-6559
Fabiola Cortés-MendozaDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Angel J Ruiz-MorenoDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Cecilia Mata-CruzDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Mireya Velázquez-PaniaguaDepartment of Physiology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Nohemí Salinas-JazmínDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Martín González-AndradeDepartment of Biochemistry, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Marco A Velasco-VelázquezDepartment of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-9717-0265

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías A1-S-18285Consejo Nacional de Humanidades, Ciencias y Tecnologías Cátedras CONAHCYT 639Universidad Nacional Autónoma de México LANCAD-UNAM-DGTIC-313Universidad Nacional Autónoma de México PAPIIT-UNAM IN206622
6 · The paper itself

Abstract

CD36 is a transmembrane glycoprotein that facilitates the uptake of fatty acids and oxidized low-density lipoproteins. CD36 is overexpressed in various types of cancer and CD36

Indexed as

CD36 AntigensBinding SitesCell SurvivalDrug Evaluation, PreclinicalHep G2 CellsHumansLipoproteins, LDLMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingSmall Molecule LibrariesStructure-Activity RelationshipCD36 AntigensCD36 protein, humanLipoproteins, LDLoxidized low density lipoproteinSmall Molecule LibrariesCD36computer‐aided drug discoveryconsensus dockinghepatocellular carcinomapalmitic acid

Identifiers

PMID41271444
PMCPMC12638226

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.