Evidence map›Paper›PMID 41271383›Full record

ArticleJACC. Case reports2025

Takotsubo Syndrome Following Pulmonary Vein Isolation With Pulse Field Ablation.

Nobunari Tomura, Keitaro Senoo, Yusuke Kakei, Kohei Kawai, Masahiro Makino, Jun Munakata, Hirokazu Shiraishi, Satoaki Matoba

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nobunari TomuraDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Keitaro SenooDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan; Department of Cardiac Arrhythmia Research and Innovation, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan. Electronic address: k-senoo@koto.kpu-m.ac.jp.
Yusuke KakeiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kohei KawaiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Masahiro MakinoDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Jun MunakataDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Hirokazu ShiraishiDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan; Department of Cardiac Arrhythmia Research and Innovation, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Satoaki MatobaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan; Department of Cardiac Arrhythmia Research and Innovation, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTakotsubo syndrome (TTS) is triggered by emotional or physical stress and characterized by transient left ventricular wall motion abnormalities in the absence of coronary culprit lesion. CASE SUMMARY: A 76-year-old woman underwent pulse field ablation (PFA) for paroxysmal atrial fibrillation. While ST-segment elevation and cardiac dysfunction were observed during the procedure, emergent coronary angiography showed no significant stenosis. The following day, left ventricular wall motion was almost normalized with T-wave inversion and prolonged QT interval. She was diagnosed with TTS due to PFA and had a favorable course with conservative treatment. DISCUSSION: This is the first report of TTS after pulmonary vein isolation with PFA. We hypothesize that it may result from stimulating sympathetic nerves caused by diaphragmatic contraction, myocardial injury, and ganglionated plexi modification according to PFA. TAKE-HOME MESSAGE: TTS should be recognized as a PFA complication, suggesting the importance to assess the intraoperative electrocardiography changes and cardiac function.

Indexed as

atrial fibrillationpulmonary vein isolationpulse field ablationTakotsubo syndrome

Identifiers

PMID41271383
PMCPMC12790221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.