Evidence map›Paper›PMID 41271381›Full record

ArticleJACC. Case reports2025

Thrombolysis of Acute ST-Segment Elevation Myocardial Infarction With Concurrent Polytrauma.

Matthew Y Lim, Kieran Macleod, Kapil Kumar, Ashlee Jeffries, John Floridis, Daniel Y Ellis, Karen Teo, John F Beltrame, Peter J Psaltis, Jessica A Marathe

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthew Y LimAdelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia; Department of Cardiology, The Royal Adelaide Hospital, Adelaide, Australia; Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.
Kieran MacleodTrauma Service, The Royal Adelaide Hospital, Adelaide, Australia.
Kapil KumarTrauma Service, The Royal Adelaide Hospital, Adelaide, Australia.
Ashlee JeffriesDepartment of Cardiology, The Royal Adelaide Hospital, Adelaide, Australia.
John FloridisTrauma Service, The Royal Adelaide Hospital, Adelaide, Australia; MedSTAR South Australian Ambulance Service, Adelaide, Australia.
Daniel Y EllisAdelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia; Trauma Service, The Royal Adelaide Hospital, Adelaide, Australia; MedSTAR South Australian Ambulance Service, Adelaide, Australia.
Karen TeoDepartment of Cardiology, The Royal Adelaide Hospital, Adelaide, Australia.
John F BeltrameAdelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia; Department of Cardiology, The Royal Adelaide Hospital, Adelaide, Australia.
Peter J PsaltisAdelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia; Department of Cardiology, The Royal Adelaide Hospital, Adelaide, Australia; Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia.
Jessica A MaratheAdelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia; Department of Cardiology, The Royal Adelaide Hospital, Adelaide, Australia; Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia. Electronic address: jessica.marathe@sa.gov.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTrauma-related myocardial infarction (MI) is rare. In regional and rural settings, ST-segment elevation myocardial infarction (STEMI) may necessitate systemic thrombolysis despite concurrent relative contraindications. CASE SUMMARY: A 47-year-old woman experienced an anterior STEMI immediately following a motor vehicle accident in a regional area. Given definitive care was at least 3 hours away, multidisciplinary consultation was undertaken, and administration of systemic thrombolysis was recommended. Successful coronary reperfusion was achieved, but the patient developed internal iliac artery bleeding requiring embolization. Coronary angiography revealed a mild left anterior descending artery stenosis. Cardiac magnetic resonance imaging confirmed MI with evidence of microvascular obstruction, late gadolinium enhancement, and myocardial edema in the territory of the left anterior descending artery. DISCUSSION: This is to our knowledge the only reported case of systemic thrombolysis for trauma-related MI in the past 30 years. TAKE-HOME MESSAGE: Multidisciplinary collaboration in regional and rural settings is important to ensure optimal outcomes where relative contraindications to thrombolysis may exist.

Indexed as

acute coronary syndromemyocardial infarctionrural medicinethrombolysistrauma

Identifiers

PMID41271381
PMCPMC12790234

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.